Di-tert-butylphosphin
di-tert-butylphosphine
CAS: 819-19-2
Molecular Formula: C8H19P
Di-tert-butylphosphin - Names and Identifiers
| Name | di-tert-butylphosphine |
| Synonyms | (tert-C4H9)2PH Di-t-butylphosphine DI-T-BUTYLPHOSPHINE Di-tert-butylphosphin DI-TERT-BUTYLPHOSPHINE di-tert-butylphosphine Di-tert-butyl-phosphane Phosphine, di-tert-butyl- Dibutylphosphinewtinhexane |
| CAS | 819-19-2 |
| EINECS | 628-263-2 |
| InChI | InChI=1/C8H19P/c1-7(2,3)9-8(4,5)6/h9H,1-6H3 |
| InChIKey | CRHWEIDCXNDTMO-UHFFFAOYSA-N |
Di-tert-butylphosphin - Physico-chemical Properties
| Molecular Formula | C8H19P |
| Molar Mass | 146.21 |
| Density | 0.79g/mLat 25°C(lit.) |
| Melting Point | -17°C |
| Boling Point | 165℃ |
| Flash Point | −1°F |
| Vapor Presure | 2.5mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear colorless |
| BRN | 1918492 |
| Storage Condition | Flammables area |
| Stability | Stability Pyrophoric - spontaneously combustible in air. Highly flammable. Note low flashpoint. Air-sensitive. Incompatible with oxidizing agents. |
| Sensitive | air sensitive |
Di-tert-butylphosphin - Risk and Safety
| Risk Codes | R17 - Spontaneously flammable in air R34 - Causes burns R48/20/22 - R41 - Risk of serious damage to eyes R40 - Limited evidence of a carcinogenic effect R39/23/24/25 - R37/38 - Irritating to respiratory system and skin. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2845 4.2/PG 1 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 1-10-13 |
| TSCA | No |
| HS Code | 29319090 |
| Hazard Class | 4.2 |
| Packing Group | I |
Di-tert-butylphosphin - Introduction
di-tert-butylphosphine(di-tert-butylphosphine) is an organophosphorus compound with the chemical formula (CH3)3C-CH2-PH2. The following is a description of the nature, use, preparation and safety information of the di-tert-butylphosphine:
Nature:
1. appearance: colorless liquid or solid.
2. Melting point: about 22-23°C.
3. Boiling point: about 157°C.
4. Solubility: Soluble in non-polar organic solvents, such as benzene, toluene and n-heptane, insoluble in water.
5. Stability: Stable at room temperature, but slow oxidation reaction with air.
Use:
1. catalyst: di-tert-butylphosphine is commonly used as a ligand in organic synthesis for catalytic reactions such as hydrogenation, carbonylation, olefin cyclization, etc.
2. metal coordination chemistry: it can form complexes with transition metals for catalytic asymmetric synthesis and carbonyl reduction reactions.
3. Hybrid ligands: Hybrid ligands can be formed with other organic phosphine compounds to construct new multifunctional catalysts.
Preparation Method:
di-tert-butylphosphine can be prepared by reacting tert-butyl magnesium bromide with phosphine trichloride. The reaction is usually carried out under anhydrous conditions, and the product is purified by cooling and distillation.
Safety Information:
1. di-tert-butylphosphine has low toxicity, but still need to pay attention to the correct operation mode and protective measures.
2. contact will irritate the skin and eyes, should avoid direct contact. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance if necessary.
3. in the process of operation should avoid inhalation of its vapor, to ensure good ventilation.
4. should be stored in a cool, dry, well-ventilated place, avoid contact with oxygen and water.
Nature:
1. appearance: colorless liquid or solid.
2. Melting point: about 22-23°C.
3. Boiling point: about 157°C.
4. Solubility: Soluble in non-polar organic solvents, such as benzene, toluene and n-heptane, insoluble in water.
5. Stability: Stable at room temperature, but slow oxidation reaction with air.
Use:
1. catalyst: di-tert-butylphosphine is commonly used as a ligand in organic synthesis for catalytic reactions such as hydrogenation, carbonylation, olefin cyclization, etc.
2. metal coordination chemistry: it can form complexes with transition metals for catalytic asymmetric synthesis and carbonyl reduction reactions.
3. Hybrid ligands: Hybrid ligands can be formed with other organic phosphine compounds to construct new multifunctional catalysts.
Preparation Method:
di-tert-butylphosphine can be prepared by reacting tert-butyl magnesium bromide with phosphine trichloride. The reaction is usually carried out under anhydrous conditions, and the product is purified by cooling and distillation.
Safety Information:
1. di-tert-butylphosphine has low toxicity, but still need to pay attention to the correct operation mode and protective measures.
2. contact will irritate the skin and eyes, should avoid direct contact. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance if necessary.
3. in the process of operation should avoid inhalation of its vapor, to ensure good ventilation.
4. should be stored in a cool, dry, well-ventilated place, avoid contact with oxygen and water.
Last Update：2024-04-10 22:29:15
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View History
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