Diethyl(aminomethylene)malonate

Diethyl(aminomethylene)malonate - Names and Identifiers

Name	Diethyl aminomethylenemalonate
Synonyms	DIETHYL AMINOMETHYLENE Diethyl aminomethylenemalonate DIETHYL AMINOMETHYLENEMALONATE Diethyl(aminomethylene)malonate Diethyl 2-(aMinoMethylene)Malonate diethyl (aminomethylidene)propanedioate ETHYL 3-AMINO-2-CARBETHOXY 2-PROPENOATE Aminomethylenemalonic acid diethyl ester diethyl 2-(aminomethylidene)propanedioate diethyl 2-(azanylmethylidene)propanedioate 2-(aminomethylene)malonic acid diethyl ester
CAS	6296-99-7
InChI	InChI=1/C8H13NO4/c1-3-12-7(10)6(5-9)8(11)13-4-2/h5H,3-4,9H2,1-2H3

Diethyl(aminomethylene)malonate - Physico-chemical Properties

Molecular Formula	C8H13NO4
Molar Mass	187.19
Density	1.136±0.06 g/cm3(Predicted)
Melting Point	56-59°C
Boling Point	114°C 1mm
Flash Point	114°C/1mm
Vapor Presure	0.0103mmHg at 25°C
BRN	1708651
pKa	2.51±0.70(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.471
MDL	MFCD01075695

Diethyl(aminomethylene)malonate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3335

Diethyl(aminomethylene)malonate - Introduction

Diethyl aminomethylenemalonate is an organic compound with the chemical formula C10H17NO4.

Nature:
1. appearance: it is a colorless liquid.
2. Solubility: It is soluble in water and most organic solvents.
3. Stability: It is stable at room temperature, but may decompose into harmful gases, such as ammonia and carbon dioxide.

Use:
1. Diethyl aminomethylenemalonate is widely used in organic synthesis as a donor of C3 units lacking gradient.
2. It can be used to synthesize organic compounds such as drugs and pesticides.
3. It can also be used as dye intermediates, surfactants and coating additives.

Preparation Method:
Diethyl aminomethylenemalonate can be synthesized by the following steps:
1. Reaction First, dehydration condensation of oxalic acid is carried out to obtain diethyl acrylate.
2. reacting diethyl acrylate with amine to generate Diethyl aminomethylenemalonate.

Safety Information:
1. Diethyl aminomethylenemalonate is irritating, avoid contact with skin, eyes and respiratory tract during use.
2. Avoid contact with high temperature, open flame and oxidant to avoid combustion or explosion.
3. storage should be sealed stored in a cool, dry place, away from the fire and flammable materials.

Last Update：2024-04-09 02:00:47