Difluoro-4-Methoxyphenylboronic

Difluoro-4-Methoxyphenylboronic - Names and Identifiers

Name	(2,6-difluoro-4-methoxyphenyl)boronic acid
Synonyms	Difluoro-4-Methoxyphenylboronic 26-Difluoro-4-MethoxyphenylboronicAci 6-DIFLUORO-4-METHOXYPHENYLBORONIC ACID 2,6-Difluoro-4-methoxyphenylboronic acid 2 6-DIFLUORO-4-METHOXYPHENYLBORONIC ACID 2,6-Difluoro-4-methoxybenzeneboronic acid (2,6-difluoro-4-methoxyphenyl)boronic acid Boronic acid, (2,6-difluoro-4-methoxyphenyl)- 2,6-Difluoro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
CAS	406482-20-0
InChI	InChI=1/C7H7BF2O3/c1-13-4-2-5(9)7(8(11)12)6(10)3-4/h2-3,11-12H,1H3

Difluoro-4-Methoxyphenylboronic - Physico-chemical Properties

Molecular Formula	C7H7BF2O3
Molar Mass	187.94
Density	1.35g/cm³
Melting Point	125-130°C(lit.)
Boling Point	269.3°C at 760 mmHg
Flash Point	116.7°C
Vapor Presure	0.00362mmHg at 25°C
Appearance	White solid
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.485
MDL	MFCD05664299
Use	Involvement in the Suzuki and Stille coupling reaction for the synthesis of antithrombotic drugs

Difluoro-4-Methoxyphenylboronic - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

Difluoro-4-Methoxyphenylboronic - Introduction

(2,) boronic acid is an organic compound with the chemical formula C7H7BF2O3. It is a white to pale yellow solid with low solubility.

The compound is mainly used as an important intermediate in organic synthesis. It has similar inhibitory activity to protease and has potential applications in drug research and development. It can also be used as a precursor for the research and synthesis of boronic acid compounds, including supramolecular chemistry, coordination chemistry and the construction of heterocyclic compounds.

(2,) The preparation of boronic acid can usually be obtained from the reaction of para-methoxydibenzene (2,6-difluororo-4-methoxyphenol) and triphenylboron (triphenylborane). Under certain conditions, the two compounds react in an organic solvent to produce the target product.

Regarding safety information,(2,) boronic acid generally has low toxicity when used correctly. However, as an organic synthesis reagent, it should be used in accordance with laboratory safety procedures and follow the relevant safety operating guidelines. Avoid contact with skin and eyes, avoid inhalation or ingestion. During use, good ventilation should be ensured and appropriate protective equipment, such as safety glasses and gloves, should be worn. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:13:35