Dinoleine
5,7-Diiodo-8-quinolinol
CAS: 83-73-8
Molecular Formula: C9H5I2NO
Dinoleine - Names and Identifiers
Dinoleine - Physico-chemical Properties
| Molecular Formula | C9H5I2NO |
| Molar Mass | 396.95 |
| Density | 2.3013 (estimate) |
| Melting Point | >200 °C (dec.) (lit.) |
| Boling Point | 370.95°C (rough estimate) |
| Storage Condition | 2-8℃ |
| MDL | MFCD00006789 |
| Physical and Chemical Properties | Chemical properties: yellowish to yellowish brown fine crystalline powder. The melting point is about 214 ℃ (decomposition). Slightly soluble in ethanol, very slightly soluble in water. Odorless, tasteless. |
| Use | Uses as anti-Amoeba, antiseptic, metal chelating agent, cation analysis reagent. Diiodoquinoline, quinoiodoform and chloroiodoquinoline are halogenated 8-hydroxyquinoline intestinal anti-amoebic agents, which are effective for amoebic dysentery and have no effect on extraintestinal amoebic protozoa. In recent years, foreign reports of this class of drugs can cause subacute spinal optic neuropathy, so it has been banned in Japan and the United States. However, the disease caused by diiodoquinoline is less common than that caused by chloroiodoquinoline. |
Dinoleine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 3249 |
Dinoleine - Upstream Downstream Industry
Dinoleine - Security information
| dangerous goods mark | Xn |
| hazard category code | 22-41 |
| safety instructions | 26-36/37/39 |
| dangerous goods transport number | 3249 |
| WGK Germany | 3 |
| RTECS number | VC5775000 |
| HazardClass | 6.1( B ) |
| PackingGroup | III |
| customs code | 29334900 |
| toxic substance data | 83-73-8(Hazardous Substances Data) |
| Toxicity | LD50 intravenous in mouse: 56mg/kg |
Last Update：2024-04-10 22:29:15
Dinoleine - Uses and synthesis methods
| biological activity | Diiodohydroxyquinoline (Iodoquinol) is a local drug, quinoline derivative, with antibacterial properties. |
| chemical properties | yellowish to yellowish brown fine crystalline powder. The melting point is about 214 ℃ (decomposition). Slightly soluble in ethanol, very slightly soluble in water. Odorless, tasteless. |
| use | used as anti-amoebic drugs, antiseptic drugs, metal chelating agents, cationic analysis reagents. Diiodoquinoline, quinodoform and chloroiodoquinoline are halogenated 8-hydroxyquinoline intestinal antiamoebic drugs, which are effective against amoebic dysentery and have no effect on exoamoeba. In recent years, it has been reported abroad that this class of drugs can cause subacute spinal optic neuropathy, so it has been banned in Japan and the United States. However, diiodoquinoline is less common than chloroiodoquinoline. |
| production method | is obtained from 8-hydroxyquinoline by iodination. |
Last Update：2024-04-09 19:04:55
Dinoleine - Nature
| melting point | >200°C (dec.) (lit.) |
| boiling point | 370.95°C (rough estimate) |
| density | 2.3013 (estimate) |
| acidity coefficient (pKa) | pKa 8.0 (Uncertain) |
| Merck | 14,5042 |
| InChIKey | UXZFQZANDVDGMM-UHFFFAOYSA-N |
Last Update：2024-04-09 15:16:15
Supplier List
Spot supply
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Spot supply
Product Name: 5,7-Diiodo-8-hydroxyquinoline Visit Supplier Webpage Request for quotationCAS: 83-73-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 5,7-Diiodo-8-quinolinol Request for quotation
CAS: 83-73-8
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
WhatsApp: 13605431940
CAS: 83-73-8
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
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View History
Raw Materials for Dinoleine
8-Hydroxyquinoline
Potassium iodide
[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] hydrogen succinate
Metronidazole
Water
Hydrochloric acid
Succinic acid
Potassium iodide
[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] hydrogen succinate
Metronidazole
Water
Hydrochloric acid
Succinic acid
Downstream Products for Dinoleine