Domin

Name	TALIPEXOLE
Synonyms	Domin Talipexol TALIPEXOLE Talipexolum Talipexol [spanish] 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine
CAS	101626-70-4

Molecular Formula	C10H15N3S
Molar Mass	209.31
Density	1.167±0.06 g/cm3(Predicted)
Boling Point	364.6±37.0 °C(Predicted)
pKa	7.22±0.20(Predicted)
Storage Condition	Room Temprature
Physical and Chemical Properties	Talikol dihydrochloride (Talipexole Dihydrochloride):C10H15N3S?2HCl. [36085-73-1]. Melting point 245 ℃ (decomposition).

Overview	Tagrisso (6-allyl-2-amino-5, 6,7, 8-tetrahydro-4h-thiazole [4,5-d]-Aza-dihydrochloride) is a selective dopamine D2 receptor agonist, it inhibits dopamine release from uninjured areas of dopamine nerve endings and reduces dopaminergic neurotransmission, I .e., by selectively stimulating dopamine D2 receptors in the postsynaptic membrane of the striatum, thereby producing an anti-Parkinson effect.
pharmacological action	tamoxifen has both α2-adrenergic receptor and selective dopamine D2 receptor agonist activity, it inhibits dopamine release from intact areas of dopamine nerve endings and reduces dopaminergic nerve conduction. Tamoxifen is effective in all major PD symptoms in subjects and is effective in reducing the severity of failure and ameliorating side effects such as circadian fluctuations and dyskinesia.
Use	α1-D2 agonist. For the treatment of Parkinson's disease.
production method	the compound (I) and thiourea are condensed and cyclized to obtain tacrolimus.

Last Update：2024-04-10 22:39:43

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Product Name: TALIPEXOLE Visit Supplier Webpage Request for quotation
CAS: 101626-70-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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