Name | Pravastatin |
Synonyms | ELISOR KOPOSTAT MEVALOTIN PRAVACHOL PRAVASTATIN Pravastatin PRAVASELECT EPTASTATIN SODIUM (3R,5S)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid 1-naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[[(2S)-2-methyl-1-oxobutyl]oxy]-, (betaR,deltaR,1S,2S,6S,8S,8aR)- (3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid (BETA R,DELTA R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-1-NAPHTHALENEHEPTANOIC ACID MONOSODIUM SALT |
CAS | 81093-37-0 |
InChI | InChI=1/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16?,17+,18+,19-,20-,22-/m0/s1 |
Molecular Formula | C23H36O7 |
Molar Mass | 424.53 |
Density | 1.21±0.1 g/cm3(Predicted) |
Melting Point | 171.2-173°C |
Boling Point | 634.5±55.0 °C(Predicted) |
Flash Point | 213.2°C |
Solubility | H2O: 19mg/mL |
Vapor Presure | 9.15E-19mmHg at 25°C |
Appearance | powder |
Color | white |
pKa | 4.31±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.554 |
Physical and Chemical Properties | White to yellowish white powder or crystalline powder, odorless, bitter. UV absorption maximum (methanol):230,237,245nm. Lactone: C23H34O6. Colorless Flake Crystal, melting point 138-142 ℃. [Α] D 22 194.0 °(C = 0.51, methanol). UV absorption maximum (methanol):230,237,245nm. |
Use | Used as hypolipidemic, cholesterol drugs |
Risk Codes | R11 - Highly Flammable R34 - Causes burns |
Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 2 |
RTECS | QJ7185000 |
white to yellowish white powder or crystalline powder, odorless, bitter. UV absorption maximum (methanol):230, 237, 245nm.
The hydroxy compound, pravastatin, was biotransformed by ML-236B (competitive).
Japan's three companies Development, 1 9 8 9 listed in March. HMG-CoA reductase inhibitors have a reducing effect on various hyperlipidemia models. For hyperlipidemia, familial hypercholesterolemia, etc.