EOS-60441

EOS-60441 - Names and Identifiers

Name	2,3-dihydrospiro[indene-1,4'-piperidine] hydrochloride
Synonyms	EOS-60441 Spiro[indane-1,4-piperidine] HCl spiro[1,2-dihydroindene-3,4'-piperidine] Spiro[indane-1,4'-piperidine]hydrochloride 2,3-Dihydro-spiro[1H-indene-1,4'-piperidine] HCl 2,3-Dihydrospiro[indene-1,4'-piperidine] hydrochloride 2,3-dihydrospiro[indene-1,4'-piperidine] hydrochloride Spiro[1H-indene-1,4'-piperidine], 2,3-dihydro-, hydrochloride 2,3-Dihydrospiro[Indene-1,4-Piperidine] Hydrochloride(WX105031S1)
CAS	96651-85-3

EOS-60441 - Physico-chemical Properties

Molecular Formula	C13H18ClN
Molar Mass	223.74172

EOS-60441 - Risk and Safety

Hazard Class

IRRITANT

EOS-60441 - Introduction

2,3-dihydrospiro[indene-1,4 '-piperidine] hydrochloride, whose scientific name is spirocyclic ester hydrochloride, is an important intermediate in organic synthesis.

Nature:
2,3-dihydrospiro[indene-1,4 '-piperidine] hydrochloride is a compound having a solid crystalline form, and its chemical formula is C20H20ClN3O2. It is a colorless or yellowish crystal. It is soluble in water and ethanol, insoluble in ether and petroleum ether. It is stable at room temperature and may decompose at high temperatures. 2,3-dihydrospiro[indene-1,4 '-piperidine] hydrochloride has a certain toxicity.

Use:
2,3-dihydrospiro[indene-1,4 '-piperidine] hydrochloride is an important pharmaceutical intermediate that is widely used in the manufacture of pharmaceuticals and pesticides. It can be used as a raw material for anti-platelet aggregation drugs, anticoagulant drugs, analgesic drugs and antiepileptic drugs. In addition, it can also be used in the fields of synthetic dyes, photosensitizers and coatings.

Method:
The preparation of 2,3-dihydrospiro[indene-1,4 '-piperidine] hydrochloride is usually carried out by a chemical synthesis method. A common preparation method is to react indane with piperidine to give a spiro [indan-1, 4 '-piperidine] intermediate, followed by hydrochloric acid salification in the presence of hydrochloric acid to give the final product.

Safety Information:
2,3-dihydrospiro[indene-1,4 '-piperidine] hydrochloride has certain toxicity, so it is necessary to pay attention to safety during use and handling. Direct contact with skin and eyes should be avoided to prevent inhalation of dust and gases. Wear appropriate protective clothing, gloves and goggles during operation. Operate in a well-ventilated area and avoid contact with oxidants and flammable materials. If contact or inhalation occurs, immediate medical attention should be given. During use and storage, relevant safety procedures and regulations must be observed.

Last Update：2024-04-09 20:52:54