EOS-62447
1H-pyrrol-2-amine
CAS: 4458-15-5
Molecular Formula: C4H6N2
EOS-62447 - Names and Identifiers
| Name | 1H-pyrrol-2-amine |
| Synonyms | EOS-62162 EOS-62447 1H-pyrrol-2-aMine 1H-pyrrol-2-amine 2-AMino-1H-pyrrole |
| CAS | 4458-15-5 |
| InChI | InChI=1/C4H6N2/c5-4-2-1-3-6-4/h1-3,6H,5H2 |
EOS-62447 - Physico-chemical Properties
| Molecular Formula | C4H6N2 |
| Molar Mass | 82.1 |
| Density | 1.172±0.06 g/cm3(Predicted) |
| Boling Point | 259.0±13.0 °C(Predicted) |
| Flash Point | 134.3°C |
| Vapor Presure | 0.0133mmHg at 25°C |
| pKa | 19.82±0.50(Predicted) |
| Refractive Index | 1.63 |
EOS-62447 - Introduction
1H-pyrrol-2-amine(1H-pyrrol-2-amine) is an organic compound containing a pyrrole ring. Its chemical formula is C4H6N2, and its structure has a pyrrole ring and an amino group. The following is a description of the nature, use, preparation and safety information of 1H-pyrrol-2-amine:
Nature:
-Appearance: 1H-pyrrol-2-amine is a colorless to pale yellow solid.
-Solubility: It has lower solubility in water and is easier to dissolve in organic solvents such as methanol and dichloromethane.
Use:
-Pharmaceutical field: 1H-pyrrol-2-amine is commonly used as some drug synthesis intermediates. It can be used in the synthesis of drugs containing pyrrole structures, such as anticancer agents and antibacterial agents.
-Chemical research: 1H-pyrrol-2-amine can also be used as catalysts and ligands for organic synthesis reactions.
Preparation Method:
1H-pyrrol-2-amine has a variety of synthetic methods, common methods include:
1. Reaction of pyrrole and ammonia: 1H-pyrrol-2-amine can be obtained by reacting pyrrole and ammonia under appropriate reaction conditions.
2. reaction of pyrrole with aminoalcohol: 1H-pyrrol-2-amine can be obtained by reacting pyrrole with aminoalcohol analogs.
Safety Information:
- 1H-pyrrol-2-amine is relatively safe under correct use and storage. However, like most organic compounds, it should follow routine laboratory safety procedures during handling.
-Contact with 1H-pirrol-2-amine may irritate the eyes, skin and respiratory tract, so avoid direct contact during use. Wear gloves, glasses and respiratory protection if necessary.
-In case of accidental exposure or accidental ingestion or inhalation, you should seek medical treatment immediately.
Nature:
-Appearance: 1H-pyrrol-2-amine is a colorless to pale yellow solid.
-Solubility: It has lower solubility in water and is easier to dissolve in organic solvents such as methanol and dichloromethane.
Use:
-Pharmaceutical field: 1H-pyrrol-2-amine is commonly used as some drug synthesis intermediates. It can be used in the synthesis of drugs containing pyrrole structures, such as anticancer agents and antibacterial agents.
-Chemical research: 1H-pyrrol-2-amine can also be used as catalysts and ligands for organic synthesis reactions.
Preparation Method:
1H-pyrrol-2-amine has a variety of synthetic methods, common methods include:
1. Reaction of pyrrole and ammonia: 1H-pyrrol-2-amine can be obtained by reacting pyrrole and ammonia under appropriate reaction conditions.
2. reaction of pyrrole with aminoalcohol: 1H-pyrrol-2-amine can be obtained by reacting pyrrole with aminoalcohol analogs.
Safety Information:
- 1H-pyrrol-2-amine is relatively safe under correct use and storage. However, like most organic compounds, it should follow routine laboratory safety procedures during handling.
-Contact with 1H-pirrol-2-amine may irritate the eyes, skin and respiratory tract, so avoid direct contact during use. Wear gloves, glasses and respiratory protection if necessary.
-In case of accidental exposure or accidental ingestion or inhalation, you should seek medical treatment immediately.
Last Update：2024-04-09 20:49:11
