Molecular Formula | C19H24O6 |
Molar Mass | 348.39 |
Density | 1.328±0.06 g/cm3(Predicted) |
Melting Point | 267~270℃ |
Boling Point | 588.1±50.0 °C(Predicted) |
pKa | 12.22±0.70(Predicted) |
Storage Condition | 2-8℃ |
biological activity | Eurycomalactone is a natural product and is an effective NF-κB inhibitor with an IC50 value of 0.5 μM. Eurycomalactone inhibited protein synthesis and decreased cyclin D1 protein levels, but had no effect on TNFα-induced degradation of IκBα or phosphorylation levels of IKKα/β and IκBα. |
target | IC50: 0.5 μM (NF-κB) |