Echinatin
(2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
CAS: 34221-41-5
Molecular Formula: C16H14O4
Echinatin - Names and Identifiers
| Name | (2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
| Synonyms | ECHINATIN Echinatin 34221-41-5 Retrochalcone ECHINATIN(RG)(CALL) 4'-Dihydroxy-2-Methoxychalcone 4,4'-Dihydroxy-2-Methoxychalcone (E)-4,4'-Dihydroxy-2-methoxychalcone 4,4'-Dihydroxy-2-methoxy-trans-chalcone (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one (2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one 2-Propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-,(2E)- 2-propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- |
| CAS | 34221-41-5 |
| InChI | InChI=1/C16H14O4/c1-20-16-10-14(18)8-4-12(16)5-9-15(19)11-2-6-13(17)7-3-11/h2-10,17-18H,1H3/b9-5+ |
Echinatin - Physico-chemical Properties
| Molecular Formula | C16H14O4 |
| Molar Mass | 270.28 |
| Density | 1.282±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 210°C (dec.) |
| Boling Point | 509.8±50.0 °C(Predicted) |
| Flash Point | 193.3°C |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Vapor Presure | 5.16E-11mmHg at 25°C |
| Appearance | White crystalline powder |
| pKa | 7.82±0.15(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.657 |
| MDL | MFCD00075719 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from licorice root. |
Echinatin - Reference
| Reference Show more | 1. Luo Yanyan, Liu Xiaoshuan, Wang Hongli, et al. Study on the purification process of total flavonoids from licorice residue by chemical transformation method [J]. Shaanxi Journal of Traditional Chinese Medicine, 2019, 040(010):1471-1476. 2. Cai Shuhui, Zhao huachong, Jia Meng, Zhao Xiaoli, Chi Yumei, Zhang Wen, Wang Honglan, Di Liuqing. Quality Evaluation of roasted licorice based on HPLC fingerprint and multi-component quantitative analysis [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(01):118-124. 3. Chang Guanhua, thin Yingyi, Cui Jie, Xu Lulu, Zhao Ziyan, Wang Wenquan, Hou Junling. Analysis of the main chemical components of the aerial parts of licorice based on UPLC-Q-Exactive Orbitrap-MS [J]. Chinese Journal of Traditional Chinese Medicine, 2021,46(06):1449-1459. 4. Luo, Hui-Long, et al. "A systematic quality control method of Huang Qi detection: simultaneous determination of eleven flavonoids and seven triterpenoid saponins by UHPLC-MS." Analytical Methods 6.13 (2014): 4593-4601. 5. [IF = 2.896] Tian-Ming Wang et al."Simultaneous determination of 14 major components in Longhu Rendan pills by ultra-high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry."Anal Methods-Uk. 2014 Apr;6(9):2923-2929 6. [IF=2.896] Hui-Long Luo et al."A systematic quality control method of Huangqi decoction: simultaneous determination of eleven flavonoids and seven triterpenoid saponins by UHPLC-MS."Anal Methods-Uk. 2014 Jun;6(13):4593-4601 7. [IF=6.15] Zhang Feng et al."Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb-drug interactions in antiviral therapy."Acta Pharmacol Sin. 2021 Jun;:1-10 8. [IF=4.451] Zijian Wang et al."Licorice flavonoids nanoparticles prepared by liquid antisolvent re-crystallization exhibit higher oral bioavailability and antioxidant activity in rat."J Funct Foods. 2019 Jun;57:190 |
Echinatin - Reference Information
| Plant source: | Licorice |
| biological activity | Echinatin is isolated from the Chinese herbal medicine licorice, chalcone, which has liver-protecting and anti-inflammatory effects. The Echinatin causes antioxidation through electron transfer (ET) and proton transfer (PT) in aqueous solution. In rats, Echinatin can be quickly absorbed and eliminated and widely distributed, with an absolute bioavailability of about 6.81%. |
| uses | prickly licorice chalcone has anti-tumor, liver-protecting and anti-inflammatory effects. used for content determination/identification/pharmacological experiment, etc. |
Last Update：2024-04-09 20:45:29
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Spot supply
Product Name: Echinatin Visit Supplier Webpage Request for quotationCAS: 34221-41-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Echinatin Visit Supplier Webpage Request for quotationCAS: 34221-41-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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