Esclama - Names and Identifiers
Esclama - Physico-chemical Properties
Molecular Formula | C9H14N4O3
|
Molar Mass | 226.23 |
Density | 1.2673 (rough estimate) |
Melting Point | 110-111° |
Boling Point | 367.84°C (rough estimate) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Off-White to Yellow |
pKa | 6.65±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.6300 (estimate) |
In vitro study | Nimorazole significantly improves the effect of radiotherapeutic management of supraglottic and pharynx tumors and can be given without major side-effects. Nimorazole is the only such agent to have shown a significant effect in a randomized controlled trial in head and neck cancer. |
Esclama - Risk and Safety
Toxicity | LD50 orally in mice: 1530 mg/kg (Cavalleri) |
Esclama - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 4.42 ml | 22.101 ml | 44.203 ml |
5 mM | 0.884 ml | 4.42 ml | 8.841 ml |
10 mM | 0.442 ml | 2.21 ml | 4.42 ml |
5 mM | 0.088 ml | 0.442 ml | 0.884 ml |
Last Update:2024-01-02 23:10:35