Esomeprazole impurity M
5-O-DESMETHYL OMEPRAZOLE
CAS: 151602-49-2
Molecular Formula: C16H17N3O3S
Esomeprazole impurity M - Names and Identifiers
Esomeprazole impurity M - Physico-chemical Properties
| Molecular Formula | C16H17N3O3S |
| Molar Mass | 331.39 |
| Density | 1.46±0.1 g/cm3(Predicted) |
| Melting Point | 238-240°C |
| Boling Point | 630.5±65.0 °C(Predicted) |
| Solubility | Dimethylformamide, Dimethyl Sulfoxide, Ethanol, Methanol |
| Appearance | Solid |
| Color | Light-Yellow |
| pKa | 8.71±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
Esomeprazole impurity M - Reference Information
| Use | this drug is a gastric proton pump inhibitor. Omeprazole can be concentrated around the secretory tubules of parietal cells after oral administration, conversion to sulfenamide derivatives. Its sulfur atom binds to the thiol group on the H ,K-ATPase, which inactivates the H pump and reduces gastric acid secretion. The drug can also increase gastric mucosal blood flow, is conducive to the treatment of ulcer disease. It is mainly used for gastric and duodenal ulcer, reflux esophagitis and zhuoai syndrome. It is also effective for patients with poor efficacy of H2 receptor blockers. 5-o-desmethylomeprazole is an impurity of Omeprazole. |
Last Update：2024-04-09 15:16:55
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View History
Esomeprazole impurity M
NSC 104019
p-Toluamide
1-(4-methoxyphenyl)propan-2-one
1-phenylethyl
DSPE-PEG-COOH
4-BROMODIPHENYL OXIDE
8-Fluoro-4-chromanone
2-ETHOXY-4'-METHYLCHALCONE
N-[(4-methoxyphenyl)methyl]hydroxylamine
NSC 104019
p-Toluamide
1-(4-methoxyphenyl)propan-2-one
1-phenylethyl
DSPE-PEG-COOH
4-BROMODIPHENYL OXIDE
8-Fluoro-4-chromanone
2-ETHOXY-4'-METHYLCHALCONE
N-[(4-methoxyphenyl)methyl]hydroxylamine