Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate
YH239-EE
CAS: 1364488-67-4
Molecular Formula: C25H27Cl2N3O4
Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate - Names and Identifiers
Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate - Physico-chemical Properties
| Molecular Formula | C25H27Cl2N3O4 |
| Molar Mass | 504.41 |
| Density | 1.313±0.06 g/cm3(Predicted) |
| Boling Point | 763.3±60.0 °C(Predicted) |
| pKa | 13.20±0.30(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | YH239-EE inhibits the growth of p53-MDM2 of cells and wild-type p53 by inhibiting OCI-AML-3 of the interaction. Of the four AML cells (p53 wild-type OCI-AML-3 and MOLM-13,p53 mutant NB4, and p53 deleted HL60), YH239-EE induce cell cycle arrest by activating p53 and downstream targets, and cause efficient apoptosis. |
Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.983 ml | 9.913 ml | 19.825 ml |
| 5 mM | 0.397 ml | 1.983 ml | 3.965 ml |
| 10 mM | 0.198 ml | 0.991 ml | 1.983 ml |
| 5 mM | 0.04 ml | 0.198 ml | 0.397 ml |
Last Update：2024-01-02 23:10:35
Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate - Introduction
YH239-EE is a chemical compound whose chemical properties are a chlorinated aromatic hydrocarbon. Its chemical formula is C6H4Cl2 and its structural formula is ClC6H4Cl. YH239-EE is an organic solvent, colorless to slightly yellow liquid, with a special smell. It has a high volatility.
YH239-EE are widely used in industry. It is commonly used as a solvent, cleaning agent and reaction medium. Because of its excellent solubility and volatility, it is often used in chemical, electronic, ink, pigment and pharmaceutical fields.
The method for preparing YH239-EE usually includes a substitution reaction of a chlorinated aromatic hydrocarbon. The most common method is to react p-dichlorobenzene with monochlorobenzene to form YH239-EE.
Regarding safety information, YH239-EE is an organic compound, so it should be noted that it is toxic and volatile. During use, avoid direct contact with skin and eyes, and ensure that you operate in a well-ventilated environment. Suitable personal protective equipment such as gloves, protective glasses and respiratory protection should be worn. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
In addition, to ensure safe operation, please follow relevant regulations and safety guidelines, and read the product's safety data sheet (SDS) carefully before use.
YH239-EE are widely used in industry. It is commonly used as a solvent, cleaning agent and reaction medium. Because of its excellent solubility and volatility, it is often used in chemical, electronic, ink, pigment and pharmaceutical fields.
The method for preparing YH239-EE usually includes a substitution reaction of a chlorinated aromatic hydrocarbon. The most common method is to react p-dichlorobenzene with monochlorobenzene to form YH239-EE.
Regarding safety information, YH239-EE is an organic compound, so it should be noted that it is toxic and volatile. During use, avoid direct contact with skin and eyes, and ensure that you operate in a well-ventilated environment. Suitable personal protective equipment such as gloves, protective glasses and respiratory protection should be worn. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
In addition, to ensure safe operation, please follow relevant regulations and safety guidelines, and read the product's safety data sheet (SDS) carefully before use.
Last Update：2024-04-10 22:29:15
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Product Name: YH239-EE Visit Supplier Webpage Request for quotation
CAS: 1364488-67-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1364488-67-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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