Ethyl6-Fluoroindole-3-acetate - Names and Identifiers
Ethyl6-Fluoroindole-3-acetate - Physico-chemical Properties
| Molecular Formula | C12H12FNO2
|
| Molar Mass | 221.23 |
| Density | 1.261±0.06 g/cm3(Predicted) |
| Boling Point | 356.9±27.0 °C(Predicted) |
| pKa | 16.10±0.30(Predicted) |
Ethyl6-Fluoroindole-3-acetate - Introduction
Ethyl6-Fluoroindole-3-acetate is an organic compound with the chemical formula C12H11FO2. Its nature has the following characteristics:
1. Appearance: Ethyl6-Fluoroindole-3-acetate is a colorless to light yellow liquid.
2. Solubility: It can be dissolved in common organic solvents, such as ether, chloroform and dichloromethane.
3. Melting point and boiling point: The melting point of Ethyl6-Fluoroindole-3-acetate is -25 ℃, and the boiling point is 222-224 ℃.
4. Stability: It has good stability under regular storage conditions.
The main uses of Ethyl6-Fluoroindole-3-acetate are as follows:
1. Synthetic drug: It can be used as an important intermediate in organic synthesis. For example, it can be used for the improved synthesis of new drugs or known drugs in the field of synthetic medicine.
2. Research purposes: It can be used in the field of biochemistry and medicinal chemistry to explore the mode and mechanism of action of indole compounds in biological processes.
The method of preparing Ethyl6-Fluoroindole-3-acetate is usually synthesized by chemical reaction, the specific steps are as follows:
1. Under appropriate reaction conditions, the indole compound is reacted with a fluorinated reagent to introduce a fluorine atom.
2. Next, the reaction product is reacted with ethyl acetate for esterification to introduce an acetyl group into the indole ring.
3. Finally, pure Ethyl6-Fluoroindole-3-acetate was obtained by crystallization or column chromatography.
When using and handling Ethyl6-Fluoroindole-3-acetate, pay attention to the following safety information:
1. May be irritating to the eyes, skin and respiratory tract, so it is necessary to comply with the necessary safety measures.
2. Wear protective glasses and gloves when using to avoid direct contact.
3. Avoid inhaling its vapor and ensure that it is operated in a well-ventilated place.
4. Should be stored in a cool, dry place, away from the fire and oxidant.
5. When disposing of waste, comply with local environmental regulations and conduct proper disposal.
Last Update：2024-04-09 21:21:28