Name | Etimizol |
Synonyms | Etimizol Ethymisol Antiffine Ethymizol Etimizole Ethimizole Ethymisole Ethylnorantifein |
CAS | 64-99-3 |
Molecular Formula | C9H14N4O2 |
Molar Mass | 210.23 |
Density | 1.26±0.1 g/cm3(Predicted) |
Melting Point | 143-144℃ |
Boling Point | 563.4±35.0 °C(Predicted) |
pKa | 14.22±0.46(Predicted) |
Storage Condition | -20℃ |
In vivo study | The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively [2]. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude [3]. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.757 ml | 23.783 ml | 47.567 ml |
5 mM | 0.951 ml | 4.757 ml | 9.513 ml |
10 mM | 0.476 ml | 2.378 ml | 4.757 ml |
5 mM | 0.095 ml | 0.476 ml | 0.951 ml |