Ethyloxindole-6-carboxylate

Ethyloxindole-6-carboxylate - Names and Identifiers

Name	Ethyloxindole-6-carboxylate
Synonyms	Ethyloxindole-6-carboxylate 1H-Indole-2,6-dicarboxylic acid diethyl ester 1H-Indole-2,6-dicarboxylic acid, 2,6-diethyl ester 6-ETHOXYCARBONYLINDOLE-2-CARBOXYLIC ACID ETHYL ESTER
CAS	107516-75-6

Ethyloxindole-6-carboxylate - Physico-chemical Properties

Molecular Formula	C14H15NO4
Molar Mass	261.27
Density	1.240±0.06 g/cm3(Predicted)
Melting Point	119-121℃
Boling Point	420.2±25.0 °C(Predicted)
Appearance	Yellow solid
pKa	13.84±0.30(Predicted)
Storage Condition	2-8°C(protect from light)
MDL	MFCD03411566

Ethyloxindole-6-carboxylate - Introduction

Ethyloxindole-6-carboxylate is an organic compound with the chemical formula C12H11NO3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
Ethyloxindole-6-carboxylate is a white crystalline solid that is stable at room temperature. It has low solubility, is insoluble in water, and is soluble in organic solvents such as ethanol and dimethyl sulfoxide.

Use:
Ethyloxindole-6-carboxylate have a variety of applications in the field of organic synthesis. It is a derivative of indolinone and can be used as a synthetic intermediate for the preparation of biologically active compounds. It has potential applications in the field of drug development, and may be used to synthesize antibacterial, antiviral and antitumor drugs.

Method:
The preparation of Ethyloxindole-6-carboxylate can be obtained by reacting indolinone with ethyl pyruvate under alkaline conditions. First, indolinone and ethyl pyruvate are added to an alkaline solution, reacted under appropriate reaction conditions, and the reaction product is crystallized and purified to obtain the target compound.

Safety Information:
Ethyloxindole-6-carboxylate safety data is limited. Relevant laboratory safety guidelines and procedures should be followed when handling and using compounds. Due to the lack of relevant toxicological and safety data, it is recommended to take appropriate personal protective measures when using it to avoid direct contact with the skin or inhalation of its dust or vapor. If any unexpected exposure or discomfort occurs, medical advice should be sought immediately.

Last Update：2024-04-09 21:01:54