Name | Etoricoxib Impurity 10 |
Synonyms | Etoricoxib A Etoricoxib Sulfoxide Etoricoxib Impurity B IMpurity of Etoricoxib Etoricoxib Impurity 10 2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfinyl)phenyl]- 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfinylphenyl)pyridine |
CAS | 316149-01-6 |
Molecular Formula | C18H15ClN2OS |
Molar Mass | 342.84 |
Density | 1.37±0.1 g/cm3(Predicted) |
Melting Point | 122-123 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3); ethyl acetate (141-78-6)) |
Boling Point | 489.7±45.0 °C(Predicted) |
pKa | 3.75±0.12(Predicted) |
Application | etoricoxib tablets (trade name: Ankang letter), is a selective COX-2 inhibitor, has anti-inflammatory, analgesic and antipyretic effect, suitable for the treatment of osteoarthritis acute and chronic symptoms and signs, can also treat acute gouty arthritis. It is developed and manufactured by mershadong company and is currently listed in 84 countries and regions around the world, including China. Etoricoxib has been recommended by the American College of Rheumatology gout guidelines for the treatment of acute gouty arthritis. |