Name | Fluorescamine |
Synonyms | Fluram FLURAM FLURAM(R) FLUORESCAMINE Fluorescamine FLUORESCAMINE SPRAY REAGENT 4-PHENYLSPIRO[FURAN-2(3H),1'-PHTHALAN]-3,3'-DIONE 4-PHENYL SPIRO-[FURAN-2(3H),1-PHTHALAN]-3,3'-DIONE 4'-phenyl-3H,3'H-spiro[2-benzofuran-1,2'-furan]-3,3'-dione 4'-PHENYL-SPIRO[2-BENZOFURAN-1(3H),2'(3'H)-FURAN]-2',3-DIONE SPIRO[FURAN-2(3H),1'(3'H)-ISOBENZOFURAN]-3,3'-DIONE, 4-PHENYL- (1R)-4'-phenyl-3H,3'H-spiro[2-benzofuran-1,2'-furan]-3,3'-dione (1S)-4'-phenyl-3H,3'H-spiro[2-benzofuran-1,2'-furan]-3,3'-dione |
CAS | 38183-12-9 |
EINECS | 253-814-5 |
InChI | InChI=1/C17H10O4/c18-15-13(11-6-2-1-3-7-11)10-20-17(15)14-9-5-4-8-12(14)16(19)21-17/h1-10H/t17-/m1/s1 |
Molecular Formula | C17H10O4 |
Molar Mass | 278.26 |
Density | 1.2661 (rough estimate) |
Melting Point | 153-157 °C (lit.) |
Boling Point | 381.08°C (rough estimate) |
Flash Point | -17°C |
Water Solubility | Soluble in acetone, ethanol, chloroform, dimethylsulfoxide and acetonitrile. Slightly soluble in water. |
Solubility | Soluble in water (partly), ethanol, chloroform, DMSO, and acetonitrile. |
Vapor Presure | 3.71E-12mmHg at 25°C |
Appearance | White-like or light yellow powder |
Color | off-white to yellow |
Merck | 14,4158 |
BRN | 921143 |
Storage Condition | room temp |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.5447 (estimate) |
MDL | MFCD00005928 |
Use | This product is for scientific research only and shall not be used for other purposes. |
Risk Codes | R11 - Highly Flammable R36/38 - Irritating to eyes and skin. R66 - Repeated exposure may cause skin dryness or cracking R67 - Vapors may cause drowsiness and dizziness R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves. S33 - Take precautionary measures against static discharges. S29 - Do not empty into drains. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. S9 - Keep container in a well-ventilated place. S37/39 - Wear suitable gloves and eye/face protection |
UN IDs | UN 1090 3/PG 2 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29322090 |
Reference Show more | 1. Gao xianjuan, Zhang Pingping, Zheng Qixia, Wang Huaisheng, Cai Qingyun. Determination of mexiletine hydrochloride in mexiletine hydrochloride tablets by fluorometry [J]. Chemical Research and Application, 2017,29(01):94-98. 2. [IF = 4.375] Zha Quanbin et al."Preparation and Study of Folate Modified atomin Targeting microbes." J Oncol. 2022;2022:3968403 3. [IF = 9.147] Mengzhen Ding et al."The effect of fat content in food matrix on the structure, rheologic properties and digestable properties of protein." Food Hydrocolloid. 2022 May;126:107464 |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
Biological activity | Fluorescamine( Ro 20-7234) is a spiro compound and has no fluorescent properties. It can react with primary amines and form fluorescence, so it is used to detect amines and peptides. |
uses | amino acid biodegradation reagent, fluorescence detection, at PH = 9, room temperature, the derivative has high intensity fluorescence, and the reagent is hydrolyzed into a product without fluorescence. It is used for high performance liquid chromatography labeling, and can also form stable, high fluorescence, and low background complexes with primary amino groups of amino acids and proteins under mild conditions, and is used for fluorescence detection of amino acids, proteins and proteolytic enzymes. Also used in protein sequencing analysis. |