FMOC-(S)-4-METHYL-BETA-PHENYLALANINE - Names and Identifiers
FMOC-(S)-4-METHYL-BETA-PHENYLALANINE - Physico-chemical Properties
Molecular Formula | C25H23NO4
|
Molar Mass | 401.45 |
Density | 1.254±0.06 g/cm3(Predicted) |
Boling Point | 627.5±55.0 °C(Predicted) |
pKa | 4.31±0.10(Predicted) |
Storage Condition | 2-8°C |
FMOC-(S)-4-METHYL-BETA-PHENYLALANINE - Introduction
Fmoc-S-3-Amino-3-(4-methyl-phenyl)-propionic acid, also known as Fmoc-S-3-Amino-3-(4-methyl-phenyl)-propionic acid, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Molecular formula: C99, H30, NO, S
-Molecular Weight: 366.41
-melting point: 102-104 ℃
-Solubility: Soluble in common organic solvents
Use:
- Fmoc-S-3-Amino-3-(4-methyl-phenyl)-propionic acid is a commonly used aryl amino acid derivative commonly used in the synthesis of biologically active polypeptides and proteins (e. g. peptide fragments, peptide libraries, active peptides).
-It can be used as a protecting group (Fmoc protecting group) in peptide synthesis.
Preparation Method:
The preparation of Fmoc-S-3-Amino-3-(4-methyl-phenyl)-propionic acid usually involves the following steps:
1. Reaction of benzyl alcohol and aldehyde under alkaline conditions for the synthesis of aromatic hydrocarbons to obtain 4-methylphenylpropanol.
2. Conversion of 4-methylphenylpropanol to the corresponding formate in methanol.
3. under alkaline conditions, formate is Fmoc-Cl reacted with antacid reagent to obtain Fmoc-S-3-Amino-3-(4-methyl-phenyl)-propionic acid.
Safety Information:
- Fmoc-S-3-Amino-3-(4-methyl-phenyl)-propionic acid is generally stable and safe under normal use conditions.
-However, since these compounds are organic synthetic reagents, appropriate laboratory safety measures need to be taken to avoid skin contact and inhalation.
-Wear appropriate personal protective equipment, such as gloves and glasses, during use.
-According to the special nature of the chemical, it is recommended to carefully read and understand the relevant safety data sheet (SDS) and operating instructions before operation.
Last Update:2024-04-10 22:29:15