FMOC-ASN(TRT)
Fmoc-N-trityl-L-Asparagine
CAS: 132388-59-1
Molecular Formula: C38H32N2O5
FMOC-ASN(TRT) - Names and Identifiers
| Name | Fmoc-N-trityl-L-Asparagine |
| Synonyms | FMOC-ASN(TRT) Fmoc-Asn(Trt)-OH FMOC-ASN(XAN)-OH FMOC-ASN(TRT)-OH FMOC-L-ASN(TRT)-OH Fmoc-L-Asn(Trt)-OH FMOC-L-ASN(TRITYL) FMOC-ASPARAGINE(TRT) FMOC-L-ASPARGINE(TRITYL) Fmoc-N-trityl-L-Asparagine N-Fmoc-N'-trityl-L-asparagine na-fmoc-N-gamma-trityl-L-asparagine N-ALPHA-FMOC-N-GAMMA-TRITYL-L-ASPARAGINE N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(tritylamino)butanoate |
| CAS | 132388-59-1 |
| InChI | InChI=1/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/p-1/t34-/m0/s1 |
| InChIKey | KJYAFJQCGPUXJY-UUWRZZSWSA-N |
FMOC-ASN(TRT) - Physico-chemical Properties
| Molecular Formula | C38H32N2O5 |
| Molar Mass | 596.67 |
| Density | 1.271±0.06 g/cm3(Predicted) |
| Melting Point | 201-204°C(lit.) |
| Boling Point | 858.1±65.0 °C(Predicted) |
| Specific Rotation(α) | -16 º (c=1, MeOH) |
| Flash Point | 472.8°C |
| Vapor Presure | 2.26E-31mmHg at 25°C |
| Appearance | White crystalline powder |
| Color | White to Almost white |
| BRN | 4343823 |
| pKa | 3.79±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -19 ° (C=1, DMF) |
| MDL | MFCD00077049 |
FMOC-ASN(TRT) - Risk and Safety
| Risk Codes | 53 - May cause long-term adverse effects in the aquatic environment |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 2 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 2924 29 70 |
| Hazard Class | IRRITANT |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
FMOC-ASN(TRT) - Introduction
FMOC-Nγ-trityl-L-asparagine is an organic compound with the following properties:
1. Appearance: FMOC-Nγ-trityl-L-asparagine is a white crystalline solid.
2. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane.
3. Stability: relatively stable at room temperature.
The main uses of FMOC-Nγ-trityl-L-asparagine are as follows:
1. Fluorescent dye: It can be used as a fluorescent probe for biochemical research and analysis.
2. peptide synthesis: it can be used as a protecting group in peptide synthesis, by introducing FMOC group at the amino end to protect other amino or hydroxyl groups to prevent unnecessary reactions.
FMOC-Nγ-trityl-L-asparagine is prepared as follows:
In general, FMOC-Nγ-trityl-L-asparagine can be prepared by reacting N-trityl-L-asparagine with FMOC acid chloride.
Regarding safety information, you need to pay attention to the following:
1. Protective measures: When handling and using the compound, you must wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory clothing.
2. toxicity: FMOC-Nγ-trityl-L-asparagine may have certain toxicity to human body, so it should be used with caution, avoid inhalation, intake or contact with skin.
3. environmental impact: should comply with the relevant environmental laws and regulations, the proper disposal of waste, to avoid pollution to the environment.
1. Appearance: FMOC-Nγ-trityl-L-asparagine is a white crystalline solid.
2. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane.
3. Stability: relatively stable at room temperature.
The main uses of FMOC-Nγ-trityl-L-asparagine are as follows:
1. Fluorescent dye: It can be used as a fluorescent probe for biochemical research and analysis.
2. peptide synthesis: it can be used as a protecting group in peptide synthesis, by introducing FMOC group at the amino end to protect other amino or hydroxyl groups to prevent unnecessary reactions.
FMOC-Nγ-trityl-L-asparagine is prepared as follows:
In general, FMOC-Nγ-trityl-L-asparagine can be prepared by reacting N-trityl-L-asparagine with FMOC acid chloride.
Regarding safety information, you need to pay attention to the following:
1. Protective measures: When handling and using the compound, you must wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory clothing.
2. toxicity: FMOC-Nγ-trityl-L-asparagine may have certain toxicity to human body, so it should be used with caution, avoid inhalation, intake or contact with skin.
3. environmental impact: should comply with the relevant environmental laws and regulations, the proper disposal of waste, to avoid pollution to the environment.
Last Update：2024-04-09 21:21:28
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