FMOC-D-GLN(TRT)-OH
N-Fmoc-N'-trityl-D-glutamine
CAS: 200623-62-7
Molecular Formula: C39H34N2O5
FMOC-D-GLN(TRT)-OH - Names and Identifiers
| Name | N-Fmoc-N'-trityl-D-glutamine |
| Synonyms | FMOC-D-GLN(TRT) FMOC-D-GLN(TRT)-OH Fmoc-D-Gln(Trt)-OH FMOC-D-GLUTAMINE(TRT)-OH FMOC-D-GLUTAMINE(TRITYL) N-Fmoc-N'-trityl-D-glutamine FMOC-N-DELTA-TRITYL-D-GLUTAMINE N-ALPHA-FMOC-N-GAMMA-TRITYL-D-GLUTAMINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-GAMMA-TRITYL-D-GLUTAMINE N-(9-Fluorenylmethyloxycarbonyl)-N'-(triphenylmethyl)-D-glutamine |
| CAS | 200623-62-7 |
FMOC-D-GLN(TRT)-OH - Physico-chemical Properties
| Molecular Formula | C39H34N2O5 |
| Molar Mass | 610.7 |
| Density | 1.256 |
| Melting Point | 232-237°C |
| Boling Point | 873.5±65.0 °C(Predicted) |
| Solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMF (Sparingly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 3.73±0.10(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD00151924 |
FMOC-D-GLN(TRT)-OH - Risk and Safety
| WGK Germany | 3 |
| HS Code | 29242990 |
FMOC-D-GLN(TRT)-OH - Introduction
N-Fmoc-N '-trityl-D-glutamine is an organic compound, commonly abbreviated as Fmoc-Val-OH. The following is a description of its nature, use, formulation and safety information:
Nature:
N-Fmoc-N '-trityl-D-glutamine is a white or off-white crystalline powder with low solubility. It is stable at room temperature and can be stored for a long time under dry conditions.
Use:
N-Fmoc-N '-trityl-D-glutamine solid phase synthesis methods commonly used in chemical synthesis, especially in peptide synthesis. It can be used as a protecting group to protect the hydroxyl or other reactive sites in amino acids to prevent side reactions. During the synthesis, it can introduce amino acids into the peptide chain by deprotection reaction.
Method:
N-Fmoc-N '-trityl-D-glutamine can be prepared by the following steps:
1. First, N-trityl-D-glutamic acid is reacted with dibromomethane to prepare N-trityl-D-glutamic acid dibromomethyl ester.
2. Reacting N-trityl-D-glutamic acid dibromomethyl ester with Fmoc-Cl (dimethylcarbamoyl chloride) to generate N-Fmoc-N '-trityl-D-glutamine.
Safety Information:
N-Fmoc-N '-trityl-D-glutamine is a relatively safe compound under regular laboratory operating conditions. However, care should be taken to prevent inhalation or contact with the skin during use. Appropriate personal protective equipment, such as lab gloves and chemical goggles, should be worn. In addition, it is recommended to operate in a well-ventilated place and follow safe operating procedures.
Nature:
N-Fmoc-N '-trityl-D-glutamine is a white or off-white crystalline powder with low solubility. It is stable at room temperature and can be stored for a long time under dry conditions.
Use:
N-Fmoc-N '-trityl-D-glutamine solid phase synthesis methods commonly used in chemical synthesis, especially in peptide synthesis. It can be used as a protecting group to protect the hydroxyl or other reactive sites in amino acids to prevent side reactions. During the synthesis, it can introduce amino acids into the peptide chain by deprotection reaction.
Method:
N-Fmoc-N '-trityl-D-glutamine can be prepared by the following steps:
1. First, N-trityl-D-glutamic acid is reacted with dibromomethane to prepare N-trityl-D-glutamic acid dibromomethyl ester.
2. Reacting N-trityl-D-glutamic acid dibromomethyl ester with Fmoc-Cl (dimethylcarbamoyl chloride) to generate N-Fmoc-N '-trityl-D-glutamine.
Safety Information:
N-Fmoc-N '-trityl-D-glutamine is a relatively safe compound under regular laboratory operating conditions. However, care should be taken to prevent inhalation or contact with the skin during use. Appropriate personal protective equipment, such as lab gloves and chemical goggles, should be worn. In addition, it is recommended to operate in a well-ventilated place and follow safe operating procedures.
Last Update：2024-04-09 21:01:54
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Product Name: Fmoc-D-Gln(Trt)-OH Visit Supplier Webpage Request for quotationCAS: 200623-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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