Fmoc-D-Glu-NH2(Fmoc-D-Glu-NH2) is a chemical reagent with the following properties:
1. Appearance: white or almost white crystalline powder.
2. molecular formula: C21H21N3O6.
3. Molecular weight: 411.41g/mol.
4. Melting point: 192-198 degrees Celsius.
5. Solubility: Soluble in organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane.
Fmoc-D-Glu-NH2 main uses include:
1. peptide synthesis: used as a protecting group in peptide synthesis to protect the amino group of glutamic acid residue.
2. biochemical research: for the synthesis of peptides and protein modification.
The method of preparing the Fmoc-D-Glu-NH2 is as follows:
1. First, L-glutamic acid is reacted with diazinecarbonyl chloride (Fmoc-Cl) under basic conditions to obtain FMOC-glutamic acid.
2. Next, FMOC-glutamic acid is reacted with ammonia (NH3) to obtain Fmoc-D-Glu-NH2.
When using the Fmoc-D-Glu-NH2, please note the following safety information:
1. Avoid contact with skin and eyes, and use protective gloves and goggles if necessary.
2. Avoid inhaling dust and operate in a well-ventilated area.
3. If ingested or inhaled by mistake, seek medical attention immediately.