FMOC-D-PHG(3-F)-(C*CH2)OH

FMOC-D-PHG(3-F)-(C*CH2)OH - Names and Identifiers

Name	Fmoc-S-3-Amino-3-(3-fluoro-phenyl)-propionic acid
Synonyms	Fmoc-b-Phe(3-F)-OH FMOC-BETA-PHE(3-F)-OH FMOC-D-PHG(3-F)-(C*CH2)OH FMoc-3-Fluoro-L-b-phenylalanine Fmoc-S-3-Amino-3-(3-fluoro-phenyl)-propionic acid FMOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPANOIC ACID FMOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID (S)-3-(9-FLUORENYLMETHOXYCARBONYLAMINO)-3-(3-FLUORO-PHENYL)-PROPIONIC ACID (S)-3-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-(3-FLUORO-PHENYL)-PROPIONIC ACID
CAS	507472-14-2
EINECS	200-258-5

FMOC-D-PHG(3-F)-(C*CH2)OH - Physico-chemical Properties

Molecular Formula	C24H20FNO4
Molar Mass	405.42
Density	1.316±0.06 g/cm3(Predicted)
Boling Point	615.4±55.0 °C(Predicted)
pKa	4.21±0.10(Predicted)
Storage Condition	2-8°C

FMOC-D-PHG(3-F)-(C*CH2)OH - Introduction

Fmoc-S-3-Amino-3-(3-fluoro-phenyl)-propionic acid is an organic compound commonly used in chemical synthesis and protein engineering.

Its properties include:
-Molecular formula: C24H19FNO4S
-Molecular weight: 435.47g/mol
-Appearance: White crystalline powder
-Melting point: 149-151°C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane, etc., insoluble in water.

The main use of Fmoc-S-3-Amino-3-(3-fluoro-phenyl)-propionic acid is in the synthesis of peptides and proteins. As part of the protecting group, it can protect the amino group of amino acid, so as to control the chemical reaction during the synthesis of polypeptide. It can also be used in protein engineering to modify specific amino acids on the surface of proteins.

It can be prepared by reacting 3-amino -3-(3-fluorophenyl) propionic acid with Fmoc-Cl (methyl difluorocarbamate) under alkaline conditions.

Regarding safety information, Fmoc-S-3-Amino-3-(3-fluoro-phenyl)-propionic acid is a chemical, you need to pay attention to its correct use and storage. Care should be taken to avoid contact with skin, eyes and respiratory tract, and to ensure that the operation is carried out in a well-ventilated place. If accidental contact or inhalation occurs, immediately wash or seek medical help. In addition, the use and storage should comply with the relevant safety procedures and operating guidelines. In general, proper use and compliance with appropriate safety procedures can ensure the safe use of chemicals.

Last Update：2024-04-10 22:29:15