FMOC-GLN-OH
Fmoc-Gln-OH
CAS: 71989-20-3
Molecular Formula: C20H20N2O5
FMOC-GLN-OH - Names and Identifiers
| Name | Fmoc-Gln-OH |
| Synonyms | FMOC-GLN FMOC-L-GLN FMOC-GLN-OH Fmoc-Gln-OH FMOC-L-GLN-OH FMOC-GLUTAMINE Fmoc-L-glutamine FMOC-L-GLUTAMINE Nalpha-FMOC-L-Glutamine Na-(9-Fluorenylmethoxycarbonyl)-L-glutamine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-GLUTAMINE N2-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-glutamine N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMINE N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine (2S)-5-amino-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoate |
| CAS | 71989-20-3 |
| EINECS | 276-254-3 |
| InChI | InChI=1/C20H20N2O5/c21-18(23)10-9-17(19(24)25)22-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H2,21,23)(H,22,26)(H,24,25)/p-1/t17-/m0/s1 |
FMOC-GLN-OH - Physico-chemical Properties
| Molecular Formula | C20H20N2O5 |
| Molar Mass | 368.38 |
| Density | 1.3116 (rough estimate) |
| Melting Point | 220°C (dec.)(lit.) |
| Boling Point | 498.73°C (rough estimate) |
| Specific Rotation(α) | -18 º (c=1,DMF) |
| Flash Point | 377.1°C |
| Solubility | almost transparency in N,N-DMF |
| Vapor Presure | 1.47E-20mmHg at 25°C |
| Appearance | White powder |
| Color | White to Almost white |
| BRN | 4722773 |
| pKa | 3.73±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -18 ° (C=1, DMF) |
| MDL | MFCD00037137 |
| Use | Used for biochemical reagents, peptide synthesis. |
FMOC-GLN-OH - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Class | IRRITANT |
FMOC-GLN-OH - Introduction
Fmoc-Gln-OH(Fmoc-Gln-OH) is an amino acid derivative with the following properties:
Nature:
-Chemical formula: C25H22N2O6
-Molecular weight: 446.46g/mol
-Appearance: White or almost white crystal or powder
-Solubility: Fmoc-Gln-OH is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) or N,N-dimethylformamide (DMF).
Use:
-Biochemical research: Fmoc-Gln-OH can be used as a protecting group in solid phase synthesis for peptide or protein synthesis.
-Drug Development: Fmoc-Gln-OH can be used as intermediates in the synthesis of drugs or biologically active peptides.
Preparation Method:
The preparation of the Fmoc-Gln-OH can be accomplished by the following steps:
1. First, glutamine is reacted with fluoric anhydride (Fmoc-OSu) to obtain Fmoc-Gln-OH acid fluoride (Fmoc-Gln-OF).
2. Then, the Fmoc-Gln-OF is reacted with pyridine (Py) or N,N-dimethylpyrrolidone (DMAP) under basic conditions to generate Fmoc-Gln-OH.
Safety Information:
-The Fmoc-Gln-OH is generally safe under normal operating conditions, but it is still necessary to comply with laboratory safety procedures.
-Be careful to prevent contact with skin, eyes or mucous membranes, and avoid inhalation or ingestion.
-During use, you can wear appropriate personal protective equipment, such as laboratory gloves, safety glasses and laboratory clothes.
-In case of any accident or discomfort, seek medical help in time and bring detailed information on chemicals for reference.
Nature:
-Chemical formula: C25H22N2O6
-Molecular weight: 446.46g/mol
-Appearance: White or almost white crystal or powder
-Solubility: Fmoc-Gln-OH is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) or N,N-dimethylformamide (DMF).
Use:
-Biochemical research: Fmoc-Gln-OH can be used as a protecting group in solid phase synthesis for peptide or protein synthesis.
-Drug Development: Fmoc-Gln-OH can be used as intermediates in the synthesis of drugs or biologically active peptides.
Preparation Method:
The preparation of the Fmoc-Gln-OH can be accomplished by the following steps:
1. First, glutamine is reacted with fluoric anhydride (Fmoc-OSu) to obtain Fmoc-Gln-OH acid fluoride (Fmoc-Gln-OF).
2. Then, the Fmoc-Gln-OF is reacted with pyridine (Py) or N,N-dimethylpyrrolidone (DMAP) under basic conditions to generate Fmoc-Gln-OH.
Safety Information:
-The Fmoc-Gln-OH is generally safe under normal operating conditions, but it is still necessary to comply with laboratory safety procedures.
-Be careful to prevent contact with skin, eyes or mucous membranes, and avoid inhalation or ingestion.
-During use, you can wear appropriate personal protective equipment, such as laboratory gloves, safety glasses and laboratory clothes.
-In case of any accident or discomfort, seek medical help in time and bring detailed information on chemicals for reference.
Last Update：2024-04-09 21:01:54
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Product Name: Fmoc-Gln-OH Visit Supplier Webpage Request for quotationCAS: 71989-20-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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