FMOC-HISTIDINE(1-TRT)-OH
na-fmoc-im-trityl-L-histidine
CAS: 109425-51-6;128545-09-5
Molecular Formula: C40H33N3O4
FMOC-HISTIDINE(1-TRT)-OH - Names and Identifiers
| Name | na-fmoc-im-trityl-L-histidine |
| Synonyms | FMOC-HIS(TRT) Fmoc-His(Trt)-OH FMOC-HIS(TRT)-OH FMOC-L-HIS(TRITYL) FMOC-HIS(1-TRT)-OH FMOC-HIS(T-TRT)-OH FMOC-HIS(TRITYL)-OH FMOC-HISTIDINE(1-TRT)-OH N-Fmoc-N'-trityl-L-histidine FMOC-N-IM-TRITYL-L-HISTIDINE na-fmoc-im-trityl-L-histidine N(alpha)-fmoc-N(im)-trityl-L-histidine N-FMOC-3-(triphenylmethyl)-L-histidine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-1-tritylhistidine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-trityl-L-histidine N-alpha-(9-fluorenylmethyloxycarbonyl)-N-im-trityl-L-histidine N-[(9H-Fluoren-6-ylmethoxy)carbonyl]-3-(triphenylmethyl)-L-histidine (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1-trityl-1H-imidazol-5-yl)propanoate |
| CAS | 109425-51-6 128545-09-5 |
| EINECS | 439-640-4 |
| InChI | InChI=1/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-41-27-43(31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/p-1/t37-/m0/s1 |
FMOC-HISTIDINE(1-TRT)-OH - Physico-chemical Properties
| Molecular Formula | C40H33N3O4 |
| Molar Mass | 619.71 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 150-155°C(lit.) |
| Boling Point | 811.7±65.0 °C(Predicted) |
| Specific Rotation(α) | +86.0 °(D/25)(c=5%inCHCl3) |
| Flash Point | 444.7°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 7.59E-28mmHg at 25°C |
| Appearance | White lens |
| Color | White to off-white |
| BRN | 5204720 |
| pKa | 3.06±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 97 ° (C=5, CHCl3) |
| MDL | MFCD00043332 |
FMOC-HISTIDINE(1-TRT)-OH - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 2933 29 90 |
FMOC-HISTIDINE(1-TRT)-OH - Introduction
N-FMOC-3-Trityl-L-histidine is an organic compound whose chemical formula is C38H31N3O5.
In terms of properties, N-FMOC-3-trityl-L-histidine is a white to off-white solid with good solubility. Its melting point is between about 100-104 degrees Celsius.
The compound is commonly used in peptide synthesis and protein research. It can be used as a protecting group to protect the α-amino group and the side chain functional group of the amino acid in order to prevent undesired side reactions during the synthesis of the peptide chain. In addition, it can also be used as an additive to the culture medium to promote cell growth and protein expression.
The method of preparing N-FMOC-3-trityl-L-histidine is generally achieved by chemical synthesis. Specifically, 3-trityl-L-histidine can be synthesized first, and then the FMOC protecting group can be introduced thereon.
Regarding safety information, N-FMOC-3-trityl-L-histidine is generally relatively safe in routine laboratory operations, but general laboratory safety practices are still required. It can be irritating to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment. In addition, when preparing and handling, care should be taken to prevent it from contacting the fire and avoid inhalation.
In terms of properties, N-FMOC-3-trityl-L-histidine is a white to off-white solid with good solubility. Its melting point is between about 100-104 degrees Celsius.
The compound is commonly used in peptide synthesis and protein research. It can be used as a protecting group to protect the α-amino group and the side chain functional group of the amino acid in order to prevent undesired side reactions during the synthesis of the peptide chain. In addition, it can also be used as an additive to the culture medium to promote cell growth and protein expression.
The method of preparing N-FMOC-3-trityl-L-histidine is generally achieved by chemical synthesis. Specifically, 3-trityl-L-histidine can be synthesized first, and then the FMOC protecting group can be introduced thereon.
Regarding safety information, N-FMOC-3-trityl-L-histidine is generally relatively safe in routine laboratory operations, but general laboratory safety practices are still required. It can be irritating to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment. In addition, when preparing and handling, care should be taken to prevent it from contacting the fire and avoid inhalation.
Last Update：2024-04-10 22:30:50
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Product Name: Fmoc-His(Trt)-OH Request for quotation
CAS: 109425-51-6
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CAS: 109425-51-6
Tel: +86-18980427282
Email: hk999@hengkangtech.com
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QQ: 1525088774
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