FMOC-L-3-BROMOPHE

FMOC-L-3-BROMOPHE - Names and Identifiers

Name	(S)-N-FMOC-3-Bromophenylalanine
Synonyms	FMOC-PHE(3-BR)-OH FMOC-L-3-BROMOPHE Fmoc-Phe(3-Br)-OH FMOC-L-3-BROMOPHENYLALANINE Fmoc-L-3-Bromophenylalanine Fmoc-3-Bromo-L-phenylalanine FMOC-3-BROMO-L-PHENYLALANINE (S)-N-FMOC-3-Bromophenylalanine (S)-N-FMOC-3-BROMOPHENYLALANINE (S)-N-Fmoc-3-Bromophenylalanine N-(9-FLUORENYLMETHOXYCARBONYL)-3-BROMOPHENYL-L-ALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3-BROMO-L-PHENYLALANINE (S)-3-(3-BROMO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID
CAS	220497-48-3
InChI	InChI=1/C24H20BrNO4/c25-16-7-5-6-15(12-16)13-22(23(27)28)26-24(29)30-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/p-1/t22-/m0/s1

FMOC-L-3-BROMOPHE - Physico-chemical Properties

Molecular Formula	C24H20BrNO4
Molar Mass	466.32
Density	1.4220 (rough estimate)
Melting Point	144.2 °C
Boling Point	660.8±55.0 °C(Predicted)
Flash Point	353.4°C
Vapor Presure	2.31E-18mmHg at 25°C
pKa	3.70±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.6500 (estimate)

FMOC-L-3-BROMOPHE - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29223900
Hazard Class	IRRITANT

FMOC-L-3-BROMOPHE - Introduction

(S)-N-FMOC-3-Bromophenylalanine is a commonly used chemical reagent, which has the following properties and applications:

Properties:(S)-N-FMOC-3-Bromophenylalanine is a white to slightly yellow solid with a strong aroma. It is a chiral compound with only L-configuration.

uses:(S)-N-FMOC-3-Bromophenylalanine is one of the important raw materials for the synthesis of peptide compounds. It is often used in peptide chain extension reactions in solid phase synthesis as a derivative of an amino acid in the peptide chain. By protecting the hydroxyl and amino Fmoc groups, it can protect the active site in the reaction and make the synthesis more efficient and selective.

Preparation method:(S)-The preparation method of N-FMOC-3-Bromophenylalanine is more complicated. A common method is to start from L-phenylalanine. First, L-Phenylalanine is converted to its acid chloride derivative by a suitable chemical reaction. The acid chloride compound is then reacted with Fmoc-imine to produce the (S)-N-FMOC-3-Bromophenylalanine. Finally, the pure product is obtained by an appropriate purification method.

Safety Information:(S)-N-FMOC-3-Bromophenylalanine is a chemical reagent, which needs to comply with relevant laboratory operating regulations and safety measures during use. It may cause irritation to the skin, eyes and respiratory tract, so wear appropriate personal protective equipment and avoid contact. At the same time, it should be operated in a well-ventilated laboratory environment. If taken by mistake or aspiration, seek medical advice immediately.

Last Update：2024-04-09 21:11:58