FMOC-PHE(3-CN)-(C*CH2)OH

FMOC-PHE(3-CN)-(C*CH2)OH - Names and Identifiers

Name	Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid
Synonyms	FMOC-PHE(3-CN)-(C*CH2)OH FMOC-BETA-HOPHE(3-CN)-OH FMOC-3-CYANO-L-BETA-HOMOPHENYLALANINE FMOC-(S)-3-AMINO-4-(3-CYANOPHENYL)BUTANOIC ACID FMOC-(S)-3-AMINO-4-(3-CYANO-PHENYL)-BUTYRIC ACID Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid (S)-3-(FMOC-AMINO)-4-(3-CYANOPHENYL)BUTYRIC ACID N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-L-HOMO(3-CYANOPHENYL)ALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-(S)-3-AMINO-4-(3-CYANOPHENYL)BUTANOIC ACID
CAS	270065-87-7

FMOC-PHE(3-CN)-(C*CH2)OH - Physico-chemical Properties

Molecular Formula	C26H22N2O4
Molar Mass	426.46
Density	1.33±0.1 g/cm3(Predicted)
Boling Point	682.6±55.0 °C(Predicted)
pKa	4.33±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C

FMOC-PHE(3-CN)-(C*CH2)OH - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10
Hazard Class	IRRITANT

FMOC-PHE(3-CN)-(C*CH2)OH - Introduction

Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid is an organic compound commonly used as an amino acid protecting group. Its molecular formula is C21H17N3O2 and its molecular weight is 347.38.

Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid is a chiral compound, which contains an amino group and a 3-cyanophenyl group. This compound is usually a white or yellowish solid. It has high stability at room temperature, but it may decompose under strong acid, strong alkali or high temperature conditions.

Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid is mainly used for peptide synthesis in solid phase synthesis. It acts as a protective group to protect the amino function in the amino acid from unwanted side reactions during the reaction. In the synthesis of the polypeptide, the synthesis of the polypeptide is completed by linking Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid to a synthetic resin to form a starting point for protecting amino acids, and then by gradually deprotecting amino acids.

Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid is usually synthesized by organic synthesis. Specifically, the Fmoc group can be introduced by performing a functionalization reaction on butyric acid, followed by introducing a 3-cyanophenyl group by a cyanation reaction, and finally the target product can be obtained.

When using and handling Fmoc-(S)-3-Amino-4-(3-cyano-phenyl)-butyric acid, the following safety information needs to be paid attention to: Wear protective glasses and protective gloves to avoid contact with skin and inhalation of its dust. Maintain good ventilation during operation and follow proper laboratory practices. In addition, the compound should be stored in a dry, cool place and away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15