FMOC-PHE(P-I)-OH
fmoc-4-iodo-L-phenylalanine
CAS: 82565-68-2
Molecular Formula: C24H20INO4
FMOC-PHE(P-I)-OH - Names and Identifiers
| Name | fmoc-4-iodo-L-phenylalanine |
| Synonyms | FMOC-L-PHE(4-I) Fmoc-Phe(4-I)-OH FMOC-PHE(4-I)-OH FMOC-L-4-IODOPHE FMOC-PHE(P-I)-OH FMOC-P-IODO-PHE-OH FMOC-P-IODO-L-PHE-OH FMOC-P-IODO-PHENYLALANINE Fmoc-L-4-Iodophenylalanine FMOC-L-4-IODOPHENYLALANINE fmoc-4-iodo-L-phenylalanine |
| CAS | 82565-68-2 |
| InChI | InChI=1/C24H20INO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1 |
FMOC-PHE(P-I)-OH - Physico-chemical Properties
| Molecular Formula | C24H20INO4 |
| Molar Mass | 513.32 |
| Density | 1.577±0.06 g/cm3(Predicted) |
| Melting Point | 213-217°C(lit.) |
| Boling Point | 658.8±55.0 °C(Predicted) |
| Specific Rotation(α) | -10 º (c=1 in DMF) |
| Flash Point | 352.2°C |
| Vapor Presure | 2.97E-18mmHg at 25°C |
| BRN | 4592723 |
| pKa | 3.73±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Light Sensitive |
| Refractive Index | 1.668 |
| MDL | MFCD00672340 |
| Use | Synthesis of phosphorylated tyrosine, synthesis of radiolabeled polypeptides. |
FMOC-PHE(P-I)-OH - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8 |
| Hazard Class | IRRITANT |
FMOC-PHE(P-I)-OH - Introduction
fmoc-4-iodo-L-phenylalanine is an amino acid derivative containing an Fmoc protecting group and has the formula C25H19IN2O4. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: White or yellowish crystalline powder;
-Melting point: 163-168°C;
-Solubility: Soluble in organic solvents such as dichloromethane, dimethyl sulfoxide and ethanol.
Use:
fmoc-4-iodo-L-phenylalanine is a commonly used amino acid protecting group, which is often used in solid phase synthesis. It can be used for the synthesis of polypeptides, proteins and other organic compounds. It can be used in solid phase synthesis as an amino acid unit, linked together with other amino acids by forming imide bonds. It can also be used as a nuclear magnetic resonance (NMR) probe to study the structure and function of peptides and proteins.
Preparation Method:
fmoc-4-iodo-L-phenylalanine are generally prepared by chemical synthesis. Briefly, the p-iodo group can be introduced by esterification of L-phenylalanine with Fmoc-leucine followed by carbonyl intensification with leucine.
Safety Information:
fmoc-4-iodo-L-phenylalanine is usually relatively safe under normal use conditions, but some safety matters still need to be paid attention:
-May cause irritation, skin contact should be avoided;
-Take appropriate personal protective measures during operation, such as wearing gloves and goggles;
-should be operated in a well-ventilated laboratory environment;
-The operation should be carried out in accordance with the relevant laboratory safety operation procedures.
Nature:
-Appearance: White or yellowish crystalline powder;
-Melting point: 163-168°C;
-Solubility: Soluble in organic solvents such as dichloromethane, dimethyl sulfoxide and ethanol.
Use:
fmoc-4-iodo-L-phenylalanine is a commonly used amino acid protecting group, which is often used in solid phase synthesis. It can be used for the synthesis of polypeptides, proteins and other organic compounds. It can be used in solid phase synthesis as an amino acid unit, linked together with other amino acids by forming imide bonds. It can also be used as a nuclear magnetic resonance (NMR) probe to study the structure and function of peptides and proteins.
Preparation Method:
fmoc-4-iodo-L-phenylalanine are generally prepared by chemical synthesis. Briefly, the p-iodo group can be introduced by esterification of L-phenylalanine with Fmoc-leucine followed by carbonyl intensification with leucine.
Safety Information:
fmoc-4-iodo-L-phenylalanine is usually relatively safe under normal use conditions, but some safety matters still need to be paid attention:
-May cause irritation, skin contact should be avoided;
-Take appropriate personal protective measures during operation, such as wearing gloves and goggles;
-should be operated in a well-ventilated laboratory environment;
-The operation should be carried out in accordance with the relevant laboratory safety operation procedures.
Last Update：2024-04-10 22:29:15
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CAS: 82565-68-2
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QQ: 3008007409
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CAS: 82565-68-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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