FMoc-Lys(Z)
N(alpha)-fmoc-N(epsilon)-Z-L-lysine
CAS: 86060-82-4
Molecular Formula: C29H30N2O6
FMoc-Lys(Z) - Names and Identifiers
| Name | N(alpha)-fmoc-N(epsilon)-Z-L-lysine |
| Synonyms | FMoc-Lys(Z) Fmoc-Lys(Z)-OH Fmoc-L-Lys(Z)-OH Nepsilon-Fmoc-Nalpha na-fmoc-N-epsilon-cbz-L-lysine N-ALPHA-FMOC-N-EPSILON-Z-L-LYSINE Nepsilon-Fmoc-Nalpha-Cbz-L-Lysine N(alpha)-fmoc-N(epsilon)-Z-L-lysine Nα-Fmoc-Nε-Z-L-lysineNepsilon-Fmoc-Nalpha-Cbz-L-Lysine N~6~-[(benzyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-6-(((benzyloxy)carbonyl)aMino)hexanoic acid |
| CAS | 86060-82-4 |
| InChI | InChI=1/C29H30N2O6/c32-27(33)26(16-8-9-17-30-28(34)36-18-20-10-2-1-3-11-20)31-29(35)37-19-25-23-14-6-4-12-21(23)22-13-5-7-15-24(22)25/h1-7,10-15,25-26H,8-9,16-19H2,(H,30,34)(H,31,35)(H,32,33)/t26-/m0/s1 |
FMoc-Lys(Z) - Physico-chemical Properties
| Molecular Formula | C29H30N2O6 |
| Molar Mass | 502.56 |
| Density | 1.261±0.06 g/cm3(Predicted) |
| Melting Point | 110-120°C |
| Boling Point | 751.2±60.0 °C(Predicted) |
| Flash Point | 408.1°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 1.04E-23mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| BRN | 3578530 |
| pKa | 3.88±0.21(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.603 |
| MDL | MFCD00065662 |
FMoc-Lys(Z) - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29242990 |
FMoc-Lys(Z) - Reference Information
| Introduction | N'-fluorenylmethoxycarbonyl-N-benzyloxycarbonyl-L-lysine is an important drug intermediate, it is a precursor for the synthesis of luteinizing hormone (LH) analogs and can also be used for the synthesis of gonadotropin releasing hormone (GnRH) highly active analogs. |
| purposes | N'-fluorenylmethoxycarbonyl-N-benzyloxycarbonyl-L-lysine is an N-protected compound of L-lysine, used in medicine, preparation of chemical intermediates. |
| preparation method | in the presence of a base, N-fluorenylmethoxycarbonyl-N-benzyloxycarbonyl-L-lysine was obtained from the reaction of 9-fluorenylmethoxycarbonyl chloride and N6-Cbz-L-lysine, A method for preparing N'-fluorenylmethyloxycarbonyl-N-benzyloxycarbonyl-L-lysine with mild reaction conditions, high yield and wide applicability. The reaction formula for the synthesis of N'-fluorenylmethoxycarbonyl-N-benzyloxycarbonyl-L-lysine is shown below: |
Last Update：2024-04-10 22:29:15
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