Molecular Formula | C28H32O15 |
Molar Mass | 608.54 |
Density | 1.72 |
Melting Point | 149 °C |
Boling Point | 901.4±65.0 °C(Predicted) |
Flash Point | 296.7°C |
Solubility | Soluble in methanol |
Vapor Presure | 5.56E-35mmHg at 25°C |
Appearance | Yellow powder |
Color | White to Pale Yellow |
pKa | 5.71±0.40(Predicted) |
Storage Condition | 2-8°C |
Stability | Hygroscopic |
Refractive Index | 1.733 |
MDL | MFCD09754430 |
Physical and Chemical Properties | White-like crystalline powder, soluble in methanol, derived from Semen Ziziphi Spinosae. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29329990 |
Reference Show more | 1. Zhang Xurong Mao Chun Qin Cheng Xue et al. Simultaneous determination of five components in chairen capsules by HPLC [J]. Chinese patent medicine 2017(6). 2. Liu aipeng, Zheng Yuguang, Wen zishuai, etc. Comprehensive evaluation of the effect of Microwave processing on the quality of semen ziziphi spinosae based on analytic hierarchy process and multi-index [J]. Chinese herbal medicines, 2018, 041(001):84-88. 3. Wen zishuai, Li Xinrui, Mu Panpan, etc. Study on the content determination and quality grade classification standard of semen ziziphi spinosae and semen ziziphi spinosae saponin A in semen ziziphi spinosae. 4. Gao Hongning, Yin Yi, Yan Guojun. UPLC-UV-ELSD determination of semen ziziphi spinosae saponin A, semen ziziphi spinosae saponin B, spinoside and 6 '''-ferulic acid Pinosol in semen ziziphi spinosae from different habitats [J]. China Contemporary Medicine, 2021,28(06):8-12. 5. Liao Mei, Xu Yao, Lan Jinshan. Simultaneous determination of wild jujube seed saponin A, wild jujube seed saponin B and spinoxin in Lily jujube seed bag tea by HPLC-MS method [J]. China modern distance education of traditional Chinese medicine, 2021,19(03):143-146. 6. Wen Baoqing, Li Wenqing, Zhou Miaoxia, Lin kunxia, Wang Xiaodong, Qian Zhengming. Identification and analysis of chemical constituents in fushenyin by core-shell chromatography-quadrupole time-of-flight mass spectrometry [J]. Shi Zhen, National Medicine, 2020,31(06):1334-1338. 7. Li, H, Shi, J, Li, Y, et al. Purification of spinosin from Ziziphi Spinosae Semen using macroporous resins followed by preparative high-performance liquid chromatography. J Sep Sci. 2019; 42: 3134- 3140. https://doi.org/10.1002/jssc.201900433 8. [IF=3.935] Ruimei Lin et al."Global identification and determination of the major constituents in Kai-Xin-San by ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry and gas chromatography-mass spectrometry."J Pharmaceut Biomed. 2021 Nov;206 9. [IF=2.408] Fang-Tong Li et al."In Vitro Effects of Ginseng and the Seed of Zizyphus jujuba var. spinosa on Gut Microbiota of Rats with Spleen Deficiency."Chem Biodivers. 2020 Sep;17(9):e2000199 10. [IF=2.408] Fang-Tong Li et al."In Vitro Effects of Ginseng and the Seed of Zizyphus jujuba var. spinosa on Gut Microbiota of Rats with Spleen Deficiency."Chem Biodivers. 2020 Sep;17(9):e2000199 11. [IF=1.813] Zhan Liang-Hui et al."Soporific Effect of Modified Suanzaoren Decoction and Its Effects on the Expression of CCK-8 and Orexin-A."Evid-Based Compl Alt. 2020;2020:6984087 |
biological activity | Spinosyn is a neuroprotective C- glycoside flavone isolated from Zizyphus jucube seeds. Spinosyn inhibit the production and polymerization of Aβ1-42 by activating Nrf2/HO-1 pathway. |
chemical properties | white crystalline powder, soluble in methanol, derived from jujube seed. |
use | spinol has sedative, soothing and hypnotic effects. used for content determination/identification/pharmacological experiments and other pharmacological effects: it has a certain effect on insomnia and sleep difficulties |