Fluoxetine
Fluoxetine
CAS: 54910-89-3
Molecular Formula: C17H18F3NO
Fluoxetine - Names and Identifiers
| Name | Fluoxetine |
| Synonyms | FLUOXETINE Fluoxetine AURORA KA-7692 (+-)-benzenepropanamin METHYL-[3-PHENYL-3-(4-TRIFLUOROMETHYLPHENOXY)PROPYL]AMINE dl-3-(p-trifluoromethylphenoxy)-n-methyl-3-phenylpropylamine (+)or(-)-n-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine (+)or(-)-n-methyl-3-phenyl-3-(alpha,alpha,alpha-trifluoro-p-tolyl)oxy)prop |
| CAS | 54910-89-3 |
| EINECS | 611-209-7 |
| InChI | InChI=1/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 |
Fluoxetine - Physico-chemical Properties
| Molecular Formula | C17H18F3NO |
| Molar Mass | 309.33 |
| Density | 1.159±0.06 g/cm3(Predicted) |
| Melting Point | 158 °C |
| Boling Point | 395.1±42.0 °C(Predicted) |
| pKa | 10.05±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Physical and Chemical Properties | Fluoxetine Hydrochloride: c17h18f3 no? HCl. [59333-67-4]. White to off-white crystalline solid, melting point 158.4-158.9 °c. Soluble in methanol or ethanol, soluble in acetonitrile, acetone or chloroform, slightly soluble in ethyl acetate, dichloromethane or water (with soniation at pH 4.5,7.0), a few insoluble in cyclohexane, hexane or toluene. Solubility (mg/m1): methanol and ethanol> 100, acetone, acetonitrile and chloroform 33~100, dichloromethane 5~10, water 1~2, ethyl acetate 2~2.5, cyclohexane, hexane and toluene 0.5~0.67. Maximum solubility in water: 14mg/ml. UV absorption maximum (methanol):227,264,268,275nm(E1cm 29.2,29.3,21.5). Acute toxicity LD50 mice, rats (mg/kg):248,452 oral. Fluoxetine Oxalate: c17h18f3 no? C2H2O4. Crystallized from ethyl acetate-methanol, melting point 179-182 °c (decomposition). |
Fluoxetine - Reference
| Reference Show more | 1. Jina Yang, Danyang Liu, Wenbin Jin, Qisheng Zhong, Ting Zhou, A green and efficient pseudotargeted lipidomics method for the study of depression based on ultra-high performance supercritical fluid chromatography-tandem mass spectrometry, Journal of Pharmac 2. [IF=4.268] Yan-Ling Qiao et al."Uncaria rhynchophylla ameliorates unpredictable chronic mild stress-induced depression in mice via activating 5-HT1A receptor: Insights from transcriptomics."Phytomedicine. 2021 Jan;81:153436 3. [IF=4.142] Liu Danyang et al."A high coverage pseudotargeted lipidomics method based on three-phase liquid extraction and segment data-dependent acquisition using UHPLC-MS/MS with application to a study of depression rats."Anal Bioanal Chem. 2021 Jun;413(15):3975-3 4. [IF=3.935] Jina Yang et al."A green and efficient pseudotargeted lipidomics method for the study of depression based on ultra-high performance supercritical fluid chromatography-tandem mass spectrometry."J Pharmaceut Biomed. 2021 Jan;192:113646 5. [IF=3.935] Wenbin Jin et al."Determination of inflammation-related lipids in depressive rats by on-line supercritical fluid extraction-supercritical fluid chromatography-tandem mass spectrometry."J Pharmaceut Biomed. 2021 Sep;203:114210 6. [IF=3.826] Zhen‐Long Yu et al."Uncarialins J‐M from Uncaria rhynchophylla and their anti‐depression mechanism in unpredictable chronic mild stress‐induced mice via activating 5‐HT1A receptor."Chinese J Chem. 2021 May;39(5):1331-1343 7. [IF=3.645] Jina Yang et al."Enhanced pseudotargeted analysis using a segment data dependent acquisition strategy by liquid chromatography–tandem mass spectrometry for a metabolomics study of liquiritin in the treatment of depression."J Sep Sci. 2020 Jun;43(11):2088- 8. [IF=2.506] Jiang Yu et al."Purification of Crocin-I from Gardenia Yellow by Macroporous Resin Columns In-Series and Its Antidepressant-Like Effect."J Chem-Ny. 2022;2022:7651553 |
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Product Name: Fluoxetine Request for quotation
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: Fluoxetine Visit Supplier Webpage Request for quotationCAS: 54910-89-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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