Name | Fluvastatin |
Synonyms | Lipaxan FLUVASTATIN Fluvastatin FLUVASTATIN NA FLUVASTATIN SODIUM FluvastatinC24H26FN04 7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid (6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate (3S,5R,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid Methyl-(±)-(E)-7-[3'-(4'-fluoro-phenyl )-1'-(1'-methylethyl)indol-2'-yl]-3,5- dihydroxy-6- heptenoate FLUVASTATIN[METHYL-(±)-(E)-7-[3'-(4”-FLUOROPHENYL )-1'-(1”-METHYLETHYL)INDOL-2'-YL]-3,5- DIHYDROXY-6- HEPTENOATE ] |
CAS | 93957-54-1 |
EINECS | 695-664-7 |
InChI | InChI=1/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+ |
Molecular Formula | C24H26FNO4 |
Molar Mass | 411.47 |
Density | 1.23±0.1 g/cm3(Predicted) |
Melting Point | 193.9-196.9 °C |
Boling Point | 681.8±55.0 °C(Predicted) |
Flash Point | 366.1°C |
Vapor Presure | 1.6E-19mmHg at 25°C |
pKa | 4.27±0.10(Predicted) |
Storage Condition | 2-8°C |
Use | Fluvastatin (Leschol) can inhibit HMG-CoA reductase activity with IC50 of 8 nM |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.43 ml | 12.152 ml | 24.303 ml |
5 mM | 0.486 ml | 2.43 ml | 4.861 ml |
10 mM | 0.243 ml | 1.215 ml | 2.43 ml |
5 mM | 0.049 ml | 0.243 ml | 0.486 ml |