Fmoc-2-Abz-OH
N-fmoc-anthranilic acid
CAS: 150256-42-1
Molecular Formula: C22H17NO4
Fmoc-2-Abz-OH - Names and Identifiers
| Name | N-fmoc-anthranilic acid |
| Synonyms | FMOC-ANT-OH FMOC-ABZ-OH Fmoc-2-Abz-OH FMOC-2-ABZ-OH FMOC-ANTHRANILIC ACID FMOC-AMINOBENZOIC ACID N-fmoc-anthranilic acid Fmoc-2-aminobenzoic acid FMOC-2-AMINOBENZOIC ACID (9H-Fluoren-9-yl)MethOxy]Carbonyl 2-Abz-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]anthranilic Acid |
| CAS | 150256-42-1 |
| InChI | InChI=1/C22H17NO4/c24-21(25)18-11-5-6-12-20(18)23-22(26)27-13-19-16-9-3-1-7-14(16)15-8-2-4-10-17(15)19/h1-12,19H,13H2,(H,23,26)(H,24,25)/p-1 |
Fmoc-2-Abz-OH - Physico-chemical Properties
| Molecular Formula | C22H17NO4 |
| Molar Mass | 359.37 |
| Density | 1.352±0.06 g/cm3(Predicted) |
| Melting Point | 216-218°C(lit.) |
| Boling Point | 537.6±33.0 °C(Predicted) |
| Flash Point | 278.9°C |
| Water Solubility | Soluble in water or 1% acetic acid. |
| Solubility | soluble in Dimethylformamide |
| Vapor Presure | 2.17E-12mmHg at 25°C |
| Appearance | White to off-white powder |
| Color | White to off-white |
| BRN | 7659726 |
| pKa | 3.60±0.36(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| MDL | MFCD00235883 |
Fmoc-2-Abz-OH - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Class | IRRITANT |
Fmoc-2-Abz-OH - Introduction
N-fmoc-anthranilic acid, also known as N-(1-fluorenylmethoxycarbonyl)-2-aminobenzoic acid, is an organic compound. The following is a description of its nature, use, preparation and safety information:
1. Nature:
-Appearance: A white solid
-Molecular formula: C16H15NO3
-Molecular weight: 269.30g/mol
-Melting point: 120-123 degrees Celsius
2. Use:
N-fmoc-anthranilic acid is often used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as drugs, dyes and fragrances.
3. Preparation method:
The preparation method of N-fmoc-anthranilic acid usually involves the reaction of carboxylic acid and amine. One possible synthetic route is the transesterification of 2-aminobenzoic acid with fluorene formate to give N-fmoc-anthranilic acid ester, followed by ester hydrolysis to give the target product.
4. Safety Information:
- N-fmoc-anthranilic acid has no special safety hazard under regular use, it is still necessary to pay attention to personal protective measures, such as wearing standard protective equipment for scientific laboratories (such as laboratory coats, safety glasses and gloves, etc.);
-When conducting any chemical experiment, proper ventilation is necessary, and chemical ventilation equipment should be used or the laboratory should be well ventilated;
-Avoid contact with skin and eyes, and avoid inhaling the dust of the compound;
-When storing and handling N-fmoc-anthranilic acid, follow safe operating procedures and store it in a dry, sealed container at room temperature, away from heat sources and flames.
1. Nature:
-Appearance: A white solid
-Molecular formula: C16H15NO3
-Molecular weight: 269.30g/mol
-Melting point: 120-123 degrees Celsius
2. Use:
N-fmoc-anthranilic acid is often used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as drugs, dyes and fragrances.
3. Preparation method:
The preparation method of N-fmoc-anthranilic acid usually involves the reaction of carboxylic acid and amine. One possible synthetic route is the transesterification of 2-aminobenzoic acid with fluorene formate to give N-fmoc-anthranilic acid ester, followed by ester hydrolysis to give the target product.
4. Safety Information:
- N-fmoc-anthranilic acid has no special safety hazard under regular use, it is still necessary to pay attention to personal protective measures, such as wearing standard protective equipment for scientific laboratories (such as laboratory coats, safety glasses and gloves, etc.);
-When conducting any chemical experiment, proper ventilation is necessary, and chemical ventilation equipment should be used or the laboratory should be well ventilated;
-Avoid contact with skin and eyes, and avoid inhaling the dust of the compound;
-When storing and handling N-fmoc-anthranilic acid, follow safe operating procedures and store it in a dry, sealed container at room temperature, away from heat sources and flames.
Last Update：2024-04-09 02:00:42
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