Fmoc-3-(2-Thienyl)-L-alanine
(S)-N-FMOC-2-Thienylalanine
CAS: 130309-35-2
Molecular Formula: C22H19NO4S
Fmoc-3-(2-Thienyl)-L-alanine - Names and Identifiers
| Name | (S)-N-FMOC-2-Thienylalanine |
| Synonyms | FMOC-L-THA FMOC-THI-OH FMOC-ALA(2-THIENYL)-OH FMOC-L-2-THIENYLALANINE Fmoc-L-2-Thienylalanine FMOC-3-ALA(2-THIENYL)-OH (S)-N-FMOC-2-Thienylalanine Fmoc-L-3-(2-Thienyl)alanine FMOC-3-(2-THIENYL)-L-ALANINE Fmoc-3-(2-Thienyl)-L-alanine FMOC-BETA-(2-THIENYL)-ALA-OH FMOC-BETA-(2-THIENYL)-ALANINE |
| CAS | 130309-35-2 |
| InChI | InChI=1/C22H19NO4S/c24-21(25)20(12-14-6-5-11-28-14)23-22(26)27-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-11,19-20H,12-13H2,(H,23,26)(H,24,25)/t20-/m0/s1 |
| InChIKey | PXBMQFMUHRNKTG-FQEVSTJZSA-N |
Fmoc-3-(2-Thienyl)-L-alanine - Physico-chemical Properties
| Molecular Formula | C22H19NO4S |
| Molar Mass | 393.46 |
| Density | 1.2174 (rough estimate) |
| Melting Point | 218.5 °C |
| Boling Point | 623.4±55.0 °C(Predicted) |
| Flash Point | 330.8°C |
| Vapor Presure | 2.11E-16mmHg at 25°C |
| Appearance | grayish white to light beige crystalline powder |
| pKa | 3.59±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| Refractive Index | 1.5060 (estimate) |
Fmoc-3-(2-Thienyl)-L-alanine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 2934 99 90 |
| Hazard Class | IRRITANT |
Fmoc-3-(2-Thienyl)-L-alanine - Introduction
(S)-N-Fmoc-2-Thienylalanine is an organic compound with the following properties:
1. Appearance and physical properties: It is a solid, the common form is white crystalline powder. It is dissolved in a dissolving organic solvent such as methylene chloride, dimethyl sulfoxide and dimethylformamide.
2. Chemical properties: It is an aromatic compound with thiophene ring and alanine residue. It can be reduced to a free amino acid by deprotection reactions such as aminolysis.
(S)-N-Fmoc-2-Thienylalanine is mainly used in the following aspects:
1. Drug synthesis: It can be used as an important intermediate in drug synthesis. It can be used as a starting material for the synthesis of polypeptides, proteins and other biologically active compounds.
2. Biochemistry research: It can be used for polypeptide synthesis, protein expression and research, and protein structure research in biochemistry and molecular biology research.
A common method of preparing (S)-N-Fmoc-2-thiophenalanine is through chemical synthesis. Specific steps include the reaction of (S)-alanine with 2-thiophenecarboxaldehyde, followed by the introduction of a protecting group by an appropriate protecting group reaction (e. g., Fmoc protecting group reaction).
For safety information, please note the following:
1. It is an organic compound that needs to be handled carefully and needs to be operated in a well-ventilated laboratory.
2. It may be irritating to the skin, eyes and respiratory system. Avoid direct contact when contacting.
3. Wear appropriate personal protective equipment during use, such as lab gloves, safety glasses and protective masks.
4. Please ensure proper storage and disposal, avoid contact with incompatible substances, avoid fire and high temperature.
5. When disposed of, it should be disposed of in accordance with local regulations and should not be dumped into sewers or the environment at will.
1. Appearance and physical properties: It is a solid, the common form is white crystalline powder. It is dissolved in a dissolving organic solvent such as methylene chloride, dimethyl sulfoxide and dimethylformamide.
2. Chemical properties: It is an aromatic compound with thiophene ring and alanine residue. It can be reduced to a free amino acid by deprotection reactions such as aminolysis.
(S)-N-Fmoc-2-Thienylalanine is mainly used in the following aspects:
1. Drug synthesis: It can be used as an important intermediate in drug synthesis. It can be used as a starting material for the synthesis of polypeptides, proteins and other biologically active compounds.
2. Biochemistry research: It can be used for polypeptide synthesis, protein expression and research, and protein structure research in biochemistry and molecular biology research.
A common method of preparing (S)-N-Fmoc-2-thiophenalanine is through chemical synthesis. Specific steps include the reaction of (S)-alanine with 2-thiophenecarboxaldehyde, followed by the introduction of a protecting group by an appropriate protecting group reaction (e. g., Fmoc protecting group reaction).
For safety information, please note the following:
1. It is an organic compound that needs to be handled carefully and needs to be operated in a well-ventilated laboratory.
2. It may be irritating to the skin, eyes and respiratory system. Avoid direct contact when contacting.
3. Wear appropriate personal protective equipment during use, such as lab gloves, safety glasses and protective masks.
4. Please ensure proper storage and disposal, avoid contact with incompatible substances, avoid fire and high temperature.
5. When disposed of, it should be disposed of in accordance with local regulations and should not be dumped into sewers or the environment at will.
Last Update：2024-04-10 22:41:30
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Product Name: Fmoc-L-Thienylalanine Visit Supplier Webpage Request for quotation
CAS: 130309-35-2
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
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CAS: 130309-35-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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