Fmoc-3-Pentafluorophenyl-D-alanine - Names and Identifiers
Fmoc-3-Pentafluorophenyl-D-alanine - Physico-chemical Properties
Molecular Formula | C24H16F5NO4
|
Molar Mass | 477.38 |
Density | 1.471 |
Melting Point | 156-158 |
Boling Point | 602.9°C at 760 mmHg |
Flash Point | 318.4°C |
Vapor Presure | 2.2E-15mmHg at 25°C |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.582 |
Fmoc-3-Pentafluorophenyl-D-alanine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Note | Harmful/Irritant/Keep Cold |
Fmoc-3-Pentafluorophenyl-D-alanine - Introduction
Fmoc-D-Pentafluorophe is a fluorine substituted amino acid compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless solid
-molecular formula: C19H16F5NO4
-Molecular weight: 429.33g/mol
-Solubility: Soluble in organic solvents such as dichloromethane, dimethyl sulfoxide
Use:
- Fmoc-D-Pentafluorophe is an important amino acid derivative in solid phase synthesis, commonly used in peptide synthesis or solid phase synthesis of the starting agent
-It can be used as an amino acid protecting group, used to synthesize a part of the peptide chain, and has a protective effect during the synthesis process
Method:
The Fmoc-D-Pentafluorophe can be prepared by a chemical synthesis method. A particular method involves esterification of pentafluorobenzoic acid and D-alanine, followed by deprotecting groups (e. G., with a dicarbonate acidifying agent) to give the desired product.
Safety Information:
Fmoc-D-Pentafluorophe is a chemical, and the following safety precautions should be paid attention to when using it:
-Avoid contact with skin and eyes to prevent irritation or injury
-Wear appropriate personal protective equipment such as lab gloves and goggles during use and handling
-Follow appropriate laboratory procedures, including proper use, storage and handling
-Follow the regulations and recommendations of hazardous substances during use, and avoid mixing with other chemicals
Last Update:2024-04-10 22:29:15