Fmoc-4-tert-butyl-D-phenylalanine
Fmoc-D-4-tert-butyl-Phe
CAS: 252049-14-2
Molecular Formula: C28H29NO4
Fmoc-4-tert-butyl-D-phenylalanine - Names and Identifiers
| Name | Fmoc-D-4-tert-butyl-Phe |
| Synonyms | RARECHEM BK PT 0192 FMOC-D-PHE(P-TBU)-OH FMOC-D-PHE(4-TBU)-OH FMOC-D-4-TERT-BUTYL-PHE Fmoc-D-4-tert-butyl-Phe FMOC-4-T-BUTYL-D-PHENYLALANINE FMOC-D-4-TERT-BUTYLPHENYLALANINE Fmoc-D-4-tetr-Butylphenylalanine Fmoc-4-tert-butyl-D-phenylalanine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-(4-T-BUTYL)-D-PHENYLALANINE 4-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine (R)-3-(4-TERT-BUTYL-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID |
| CAS | 252049-14-2 |
| InChI | InChI=1/C28H29NO4/c1-28(2,3)19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m1/s1 |
Fmoc-4-tert-butyl-D-phenylalanine - Physico-chemical Properties
| Molecular Formula | C28H29NO4 |
| Molar Mass | 443.53 |
| Density | 1.198±0.06 g/cm3(Predicted) |
| Boling Point | 637.9±55.0 °C(Predicted) |
| Flash Point | 339.6°C |
| Vapor Presure | 3.82E-17mmHg at 25°C |
| pKa | 3.81±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.6 |
Fmoc-4-tert-butyl-D-phenylalanine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
Fmoc-4-tert-butyl-D-phenylalanine - Introduction
Fmoc-D-4-tert-butyl-Phe(Fmoc-D-4-tert-butyl-Phe) is an organic compound. Its main properties include:
1. Appearance: colorless crystal or white solid.
2. Chemical structure: It is a phenolic compound, which is obtained by the reaction of tert-butyl phenylalanine with Fmoc (9-spiro epoxy-1,3-dioxacyclododecan-6-one) group.
3. Solubility: can be dissolved in organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM), etc.
Fmoc-D-4-tert-butyl-Phe peptide synthesis and polymer chemistry commonly used in solid phase synthesis. It can be used as an amino acid unit in the solid phase synthesis of active groups for the construction of peptide sequences. In addition, it can also be used to synthesize organic compounds with special structures.
One method for preparing Fmoc-D-4-tert-butyl-Phe is to condense tert-butyl phenylalanine with Fmoc. Generally, an appropriate condensation reagent, such as diborane (B2pin2), the reaction is carried out in a suitable solvent. After the reaction, the product is obtained by appropriate extraction and purification steps.
Need to pay attention to safety matters when using the Fmoc-D-4-tert-butyl-Phe. It may be irritating to the eyes, skin and respiratory system, so it is necessary to wear appropriate protective measures, such as laboratory gloves and goggles, when handling. At the same time, attention should also be paid to the storage method to avoid contact with strong oxidants and strong acids. If necessary, it should be operated under well-ventilated laboratory conditions. Disposal shall be in accordance with local waste disposal regulations.
1. Appearance: colorless crystal or white solid.
2. Chemical structure: It is a phenolic compound, which is obtained by the reaction of tert-butyl phenylalanine with Fmoc (9-spiro epoxy-1,3-dioxacyclododecan-6-one) group.
3. Solubility: can be dissolved in organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM), etc.
Fmoc-D-4-tert-butyl-Phe peptide synthesis and polymer chemistry commonly used in solid phase synthesis. It can be used as an amino acid unit in the solid phase synthesis of active groups for the construction of peptide sequences. In addition, it can also be used to synthesize organic compounds with special structures.
One method for preparing Fmoc-D-4-tert-butyl-Phe is to condense tert-butyl phenylalanine with Fmoc. Generally, an appropriate condensation reagent, such as diborane (B2pin2), the reaction is carried out in a suitable solvent. After the reaction, the product is obtained by appropriate extraction and purification steps.
Need to pay attention to safety matters when using the Fmoc-D-4-tert-butyl-Phe. It may be irritating to the eyes, skin and respiratory system, so it is necessary to wear appropriate protective measures, such as laboratory gloves and goggles, when handling. At the same time, attention should also be paid to the storage method to avoid contact with strong oxidants and strong acids. If necessary, it should be operated under well-ventilated laboratory conditions. Disposal shall be in accordance with local waste disposal regulations.
Last Update：2024-04-09 21:11:58
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CAS: 252049-14-2
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QQ: 3008007409
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CAS: 252049-14-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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