Fmoc-D-4-Aph(cbm)
Fmoc-D-Aph(Cbm)-OH
CAS: 324017-22-3
Molecular Formula: C25H23N3O5
Fmoc-D-4-Aph(cbm) - Names and Identifiers
Fmoc-D-4-Aph(cbm) - Physico-chemical Properties
| Molecular Formula | C25H23N3O5 |
| Molar Mass | 445.47 |
| Density | 1.376±0.06 g/cm3(Predicted) |
| Melting Point | 163℃ (decomposition) |
| Boling Point | 699.1±55.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 3.82±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic |
Fmoc-D-4-Aph(cbm) - Introduction
Fmoc-D-Aph(Cbm)-OH(Fmoc-D-Aph(Cbm)-OH) is an organic compound. Here is some relevant information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C38H32N2O6
-Molecular weight: 612.68g/mol
-Melting Point: about 155-160 ℃ (decomposition)
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane and dimethylformamide (DMF)
Use:
- Fmoc-D-Aph(Cbm)-OH is an amino acid protecting group commonly used in peptide synthesis and solid phase synthesis.
-It can prevent non-specific reactions of amino acids during synthesis and protect the target amino acids.
- Fmoc-D-Aph(Cbm)-OH plays an important role in the synthesis of peptides, polymers and other organic syntheses.
Method:
-The preparation method of Fmoc-D-Aph(Cbm)-OH is more complicated, usually involving multi-step reactions and synthesis.
-A common synthesis method is: first combine 2-arylmethyl epoxy butane (Fmoc-Cbm-OH) with D-phenylalanine (D-Aph-OH) the reaction yields fluorenylmethoxycarbonyl-D-phenylalanine (Fmoc-D-Aph-OH), which is then converted Fmoc-D-Aph-OH to its amide form (Fmoc-D-Aph(Cbm)-OH) by Carbamoylation.
Safety Information:
- Fmoc-D-Aph(Cbm)-OH is generally considered to be relatively safe under regular operating conditions.
-Since the synthesis process may involve a variety of organic reagents and reaction conditions, please use it reasonably and operate in accordance with laboratory safety procedures.
-The identification, synthesis and use of this compound should be carried out by experienced chemical professionals and in accordance with the relevant safety practices.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C38H32N2O6
-Molecular weight: 612.68g/mol
-Melting Point: about 155-160 ℃ (decomposition)
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane and dimethylformamide (DMF)
Use:
- Fmoc-D-Aph(Cbm)-OH is an amino acid protecting group commonly used in peptide synthesis and solid phase synthesis.
-It can prevent non-specific reactions of amino acids during synthesis and protect the target amino acids.
- Fmoc-D-Aph(Cbm)-OH plays an important role in the synthesis of peptides, polymers and other organic syntheses.
Method:
-The preparation method of Fmoc-D-Aph(Cbm)-OH is more complicated, usually involving multi-step reactions and synthesis.
-A common synthesis method is: first combine 2-arylmethyl epoxy butane (Fmoc-Cbm-OH) with D-phenylalanine (D-Aph-OH) the reaction yields fluorenylmethoxycarbonyl-D-phenylalanine (Fmoc-D-Aph-OH), which is then converted Fmoc-D-Aph-OH to its amide form (Fmoc-D-Aph(Cbm)-OH) by Carbamoylation.
Safety Information:
- Fmoc-D-Aph(Cbm)-OH is generally considered to be relatively safe under regular operating conditions.
-Since the synthesis process may involve a variety of organic reagents and reaction conditions, please use it reasonably and operate in accordance with laboratory safety procedures.
-The identification, synthesis and use of this compound should be carried out by experienced chemical professionals and in accordance with the relevant safety practices.
Last Update：2024-04-10 22:29:15
