Fmoc-D-4-aminophe(Boc) - Names and Identifiers
Name | Fmoc-p-amino-D-Phe(Boc)-OH
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Synonyms | Boc-D-Phe(4-Nhboc)-Oh FMOC-D-4-AMINOPHE(BOC) FMOC-D-PHE(P-NHBOC)-OH FMOC-D-PHE(4-NHBOC)-OH Fmoc-D-4-aminophe(Boc) Fmoc-D-Phe(4-NHBoc)-OH Fmoc-p-amino-D-Phe(Boc)-OH FMOC-P-AMINO-D-PHE(BOC)-OH fmoc-d-4-aminophenylalanine(boc) FMOC-D-4-AMINOPHENYLALANINE(BOC) FMOC-4-(BOC-AMINO)-D-PHENYLALANINE FMOC-(BOC-4-AMINO)-D-PHENYLALANINE 4-(Boc-amino)-N-Fmoc-D-phenylalanine FMOC-P-AMINO-D-PHENYLALANINE(BOC)-OH 4-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine
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CAS | 214750-77-3
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InChI | InChI=1/C29H30N2O6/c1-29(2,3)37-28(35)30-19-14-12-18(13-15-19)16-25(26(32)33)31-27(34)36-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,30,35)(H,31,34)(H,32,33)/t25-/m1/s1 |
Fmoc-D-4-aminophe(Boc) - Physico-chemical Properties
Molecular Formula | C29H30N2O6
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Molar Mass | 502.56 |
Density | 1.280±0.06 g/cm3(Predicted) |
Boling Point | 671.0±55.0 °C(Predicted) |
Flash Point | 359.6°C |
Vapor Presure | 6.37E-19mmHg at 25°C |
Appearance | Solid |
pKa | 3.80±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.622 |
Fmoc-D-4-aminophe(Boc) - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Class | IRRITANT |
Fmoc-D-4-aminophe(Boc) - Introduction
Fmoc-p-amino-D-Phe(Boc)-OH, also known as Fmoc-p-amino-D-Phe(Boc)-OH, is an organic compound. The following is its nature, use, preparation and safety information:
Nature:
Fmoc-p-amino-D-Phe(Boc)-OH is a white solid with a protecting group Boc and a protecting group Fmoc, the molecular formula is C32H31NO6, and the molecular weight is 525.59.
Use:
Fmoc-p-amino-D-Phe(Boc)-OH is commonly used in peptide synthesis as a protecting group at the amino terminus of a peptide chain. It may allow the amino terminus to not react non-specifically during the synthesis for subsequent synthetic steps. In addition, it can also be used in the field of pharmaceutical research, such as drug development and drug interaction research.
Method:
The preparation of Fmoc-p-amino-D-Phe(Boc)-OH generally involves the reaction of 4-(Boc-amino)-D-phenylalanine with Fmoc-Cl to produce the desired product. The specific reaction conditions and procedures can be adjusted according to experimental requirements.
Safety Information:
When using and handling Fmoc-p-amino-D-Phe(Boc)-OH, the following safety precautions should be paid attention to: Avoid direct contact with skin and eyes, and use protective gloves and goggles; adequate ventilation during operation; Avoid inhalation of dust or gas from the substance. If ingestion or aspiration, should be timely medical treatment. If necessary, read the safety data sheet (SDS) of the substance for more detailed safety information.
Last Update:2024-04-09 02:00:44