Fmoc-L-2-Nitrophe - Names and Identifiers
Fmoc-L-2-Nitrophe - Physico-chemical Properties
Molecular Formula | C24H20N2O6
|
Molar Mass | 432.43 |
Density | 1.371±0.06 g/cm3 (20 ºC 760 Torr) |
Boling Point | 672.7±55.0 °C(Predicted) |
Flash Point | 360.6°C |
Vapor Presure | 5.18E-19mmHg at 25°C |
Appearance | solid |
pKa | 3.58±0.11(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.649 |
Fmoc-L-2-Nitrophe - Risk and Safety
Hazard Symbols | Xi - Irritant
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
Fmoc-L-2-Nitrophe - Introduction
Fmoc-L-2-Nitrophe is an organic compound with the following properties:
1. Appearance: white solid
2. Molecular formula: C29H23N3O6
3. Molecular weight: 509.51g/mol
4. Melting Point: 167-169 ° C
Fmoc-L-2-Nitrophe are commonly used in biochemistry and organic synthesis. It is mainly used as a protecting group for amino acids and can protect amino groups during peptide synthesis. In addition, it can also be used in pharmaceutical research and industrial preparation.
The general method for preparing Fmoc-L-2-Nitrophe is to introduce the Fmoc group onto L-2-nitrophenylalanine through a reaction. Specifically, L-2-nitrophenylalanine can be first reacted with dimethylammonium formatesulfate (DMTMM) to produce an intermediate. Then, Fmoc-Cl is added to the reaction system under basic conditions to form a Fmoc-L-2-Nitrophe. Finally, by appropriate isolation and purification steps, the target product can be obtained.
When using the Fmoc-L-2-Nitrophe, pay attention to the following safety information:
1. Fmoc-L-2-Nitrophe may cause irritation to the skin, eyes and respiratory tract, should wear appropriate protective equipment, avoid contact.
2. In the use of the process, should ensure good indoor ventilation, avoid inhalation of its steam and dust.
3. Avoid contact with strong oxidants to prevent dangerous reactions.
4. Fmoc-L-2-Nitrophe should be stored in a dark, dry and well-ventilated place, away from fire and high temperature.
5. In the use and storage process, please carefully read and comply with the relevant safety procedures and precautions.
Last Update:2024-04-09 21:00:56