Fmoc-L-3-Chlorophenylalanine

Fmoc-L-3-Chlorophenylalanine - Names and Identifiers

Name	Fmoc-L-3-Chlorophe
Synonyms	Fmoc-Phe(3-Cl)-OH FMOC-PHE(3-CL)-OH FMOC-PHE(M-CL)-OH Fmoc-L-3-Chlorophe FMOC-L-3-CHLOROPHE FMOC-L-PHE(3-CL)-OH FMOC-M-CHLORO-L-PHE-OH FMOC-L-3-CHLOROPHENYLALANINE Fmoc-L-3-Chlorophenylalanine Fmoc-3-chloro-L-phenylalanine Fmoc-3-Chloro-L-phenylalanine FMOC-3-CHLORO-L-PHENYLALANINE (L)-3-CHLOROPHENYL-N-FMOC-ALANINE
CAS	198560-44-0
InChI	InChI=1/C24H20ClNO4/c25-16-7-5-6-15(12-16)13-22(23(27)28)26-24(29)30-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1

Fmoc-L-3-Chlorophenylalanine - Physico-chemical Properties

Molecular Formula	C24H20ClNO4
Molar Mass	421.87
Density	1.337±0.06 g/cm3(Predicted)
Boling Point	640.9±55.0 °C(Predicted)
Flash Point	341.4°C
Vapor Presure	2.64E-17mmHg at 25°C
Appearance	Solid
pKa	3.70±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.637

Fmoc-L-3-Chlorophenylalanine - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

Fmoc-L-3-Chlorophenylalanine - Introduction

Fmoc-L-3-Chlorophe, often referred to simply as Fmoc-Cl-Val-OH, is a chemical compound. The following is a description of its nature, use, preparation and safety information:

Nature:
Fmoc-L-3-Chlorophe is a solid compound. It has a white to light yellow crystalline appearance and is stable at room temperature. Its chemical formula is C17H15ClNO3 and its molecular weight is 319.76g/mol.

Use:
Fmoc-L-3-Chlorophe are reagents commonly used in the field of peptide synthesis. It can be used as a reagent to protect the hydroxyl groups of amino acid side chains, thereby achieving selective protection in synthetic peptides. In addition, it can also be used in the synthesis of natural and artificial peptides, protein technology research and drug development.

Method:
In General, Fmoc-Cl-Val-OH can be synthesized by the following steps: First, react N-fluorenylmethoxycarbonyl-L-3-chlorophenetamine with an appropriate acid to generate Fmoc-Cl-Val; Then, the resulting Fmoc-Cl-Val is reacted with an appropriate hydroxide to produce the desired product Fmoc-L-3-Chlorophe.

Safety Information:
When using or operating the Fmoc-L-3-Chlorophe, pay attention to the following safety precautions:
1. May cause irritation to the eyes, skin and respiratory tract, so wear protective glasses, gloves and protective masks.
2. Avoid contact with strong oxidants to avoid possible dangerous reactions.
3. During operation, it should be carried out in a well-ventilated place to prevent inhalation or exposure to harmful gases.
4. During storage and handling, it should be sealed and kept away from fire and heat sources.
5. Seek immediate medical help if accidental contact or ingestion occurs.

Last Update：2024-04-09 21:01:54