Fmoc-L-beta-homophenylalanine
fmoc-L-beta-homophenylalanine
CAS: 193954-28-8
Molecular Formula: C25H23NO4
Fmoc-L-beta-homophenylalanine - Names and Identifiers
| Name | fmoc-L-beta-homophenylalanine |
| Synonyms | Fmoc-β-HoPhe-OH Fmoc-b-HoPhe-OH Fmoc-beta-Homophe-OH Fmoc-L-BETA-Homo-Phe-OH fmoc-L-beta-homophenylalanine Fmoc-L-beta-homophenylalanine N-Fmoc-L-beta-homophenylalanine (S)-Fmoc-3-amino-4-phenylbutyric acid (S)-3-(Fmoc-amino)-4-phenylbutanoic acid (S)-3-(Fmoc-amino)-4-phenylbutyric acid, Fmoc-L-β-homophenylalanine (3R)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid (3S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-phenylbutanoic acid |
| CAS | 193954-28-8 |
| InChI | InChI=1/C25H23NO4/c27-24(28)15-18(14-17-8-2-1-3-9-17)26-25(29)30-16-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,18,23H,14-16H2,(H,26,29)(H,27,28)/t18-/m1/s1 |
Fmoc-L-beta-homophenylalanine - Physico-chemical Properties
| Molecular Formula | C25H23NO4 |
| Molar Mass | 401.45 |
| Density | 1.254±0.06 g/cm3(Predicted) |
| Melting Point | 110-112 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
| Boling Point | 633.2±50.0 °C(Predicted) |
| Flash Point | 336.8°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 6.64E-17mmHg at 25°C |
| pKa | 4.38±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.624 |
Fmoc-L-beta-homophenylalanine - Risk and Safety
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
Fmoc-L-beta-homophenylalanine - Introduction
Fmoc-L-beta-homophenylalanine is an amino acid derivative with several properties:
Nature:
1. Appearance: White or almost white powder.
2. Molecular formula: C21H19NO4.
3. Molecular weight: 353.38g/mol.
4. Melting point: About 163-165 degrees Celsius.
5. Solubility: soluble in some organic solvents, such as dimethyl sulfoxide, dimethylformamide and dichloromethane.
Use:
Fmoc-L-β-homophenylalanine is mainly used for peptide synthesis in solid phase synthesis, as a protecting group or the introduction of other functional groups in peptide synthesis. It is a commonly used tryptophan protecting group, which can effectively protect the tryptophan group in solid phase synthesis to avoid unnecessary side reactions. In addition, Fmoc-L-β-homophenylalanine can also be used in drug research and development, biochemistry and other fields.
Method:
The preparation process of Fmoc-L-β-homophenylalanine is relatively complicated and is generally obtained by chemical synthesis. Detailed preparation procedures and conditions can be found in the relevant literature and patents.
Safety Information:
1. Fmoc-L-β-homophenylalanine generally has low toxicity and irritation under normal use conditions. However, it is still necessary to pay attention to personal protective measures, such as wearing laboratory gloves and goggles.
2. During handling and storage, avoid contact with strong oxidants and strong acids to prevent fire or explosion.
3. Chemicals should be kept away from children and stored properly to avoid ingestion or contact.
4. If ingestion or contact with skin, eyes and other parts, should immediately rinse with plenty of water, and seek medical help.
It should be noted that the above information is for reference only. Please read the relevant literature and product instructions carefully before use to ensure safe operation and correct use of chemicals.
Nature:
1. Appearance: White or almost white powder.
2. Molecular formula: C21H19NO4.
3. Molecular weight: 353.38g/mol.
4. Melting point: About 163-165 degrees Celsius.
5. Solubility: soluble in some organic solvents, such as dimethyl sulfoxide, dimethylformamide and dichloromethane.
Use:
Fmoc-L-β-homophenylalanine is mainly used for peptide synthesis in solid phase synthesis, as a protecting group or the introduction of other functional groups in peptide synthesis. It is a commonly used tryptophan protecting group, which can effectively protect the tryptophan group in solid phase synthesis to avoid unnecessary side reactions. In addition, Fmoc-L-β-homophenylalanine can also be used in drug research and development, biochemistry and other fields.
Method:
The preparation process of Fmoc-L-β-homophenylalanine is relatively complicated and is generally obtained by chemical synthesis. Detailed preparation procedures and conditions can be found in the relevant literature and patents.
Safety Information:
1. Fmoc-L-β-homophenylalanine generally has low toxicity and irritation under normal use conditions. However, it is still necessary to pay attention to personal protective measures, such as wearing laboratory gloves and goggles.
2. During handling and storage, avoid contact with strong oxidants and strong acids to prevent fire or explosion.
3. Chemicals should be kept away from children and stored properly to avoid ingestion or contact.
4. If ingestion or contact with skin, eyes and other parts, should immediately rinse with plenty of water, and seek medical help.
It should be noted that the above information is for reference only. Please read the relevant literature and product instructions carefully before use to ensure safe operation and correct use of chemicals.
Last Update：2024-04-09 19:05:47
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Product Name: Fmoc-L-beta-homophenylalanine Request for quotation
CAS: 193954-28-8
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
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CAS: 193954-28-8
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
Wechat: 13605431940
WhatsApp: 13605431940
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