Fmoc-L-threoninol - Names and Identifiers
Name | Fmoc-L-threoninol
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Synonyms | Fmoc-Thr-ol FMOC-THR-OL FMOC-L-THR-OL FMOC-THREONINOL Fmoc-L-threoninol FMOC-L-THREONINOL N-Fmoc-L-threonol N-FMOC-L-THREONINOL FMOC-(2R,3R)-2-AMINO-3-HYDROXY-1-BUTANOL N-(9-FLUORENYLMETHOXYCARBONYL)-THREONINOL 9-FLUORENYLMETHYLOXYCARBONYL-L-THREONINOL 9H-fluoren-9-ylmethyl [(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]carbamate
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CAS | 176380-53-3
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InChI | InChI=1/C19H21NO4/c1-12(22)18(10-21)20-19(23)24-11-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,12,17-18,21-22H,10-11H2,1H3,(H,20,23)/t12-,18-/m1/s1 |
Fmoc-L-threoninol - Physico-chemical Properties
Molecular Formula | C19H21NO4
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Molar Mass | 327.37 |
Density | 1.259±0.06 g/cm3(Predicted) |
Boling Point | 586.5±45.0 °C(Predicted) |
Flash Point | 308.5°C |
Vapor Presure | 1.35E-14mmHg at 25°C |
Appearance | Solid |
pKa | 11.27±0.46(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.608 |
Fmoc-L-threoninol - Introduction
Fmoc-L-threoninol is an organic compound with the following properties:
1. Appearance: A white powdery solid.
2. Solubility: soluble in organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane, etc.
3. Melting Point: about 70-75 degrees Celsius.
4. Molecular formula: C18H19NO4.
5. Molecular weight: 313.35g/mol.
Fmoc-L-threoninol is widely used in organic synthesis, mainly for the synthesis of polymers, drugs and bioactive molecules. Its main uses are as follows:
1. Protected amino group: Because the compound has a Fmoc protecting group (Zhong), it can be used to protect the amino group to avoid accidental reactions in chemical reactions.
2. Oriented functional group reaction: through SN2 substitution reaction with other compounds, guide the synthesis of specific functional groups, such as carboxylic acids, aldehydes and ketones.
3. Drug synthesis: In the process of drug synthesis, specific functional groups can be introduced as intermediates or starting compounds.
The production method of Fmoc-L-threoninol is generally achieved by a chemical synthesis method. The specific steps include reacting 1,3-butanediol with N-fluorophthalimide (N-Fmoc) to produce the target product.
Regarding safety information, Fmoc-L-threoninol is a chemical and necessary safety measures need to be taken during handling. Direct contact with skin and eyes should be avoided and it should be ensured that the operation is carried out in a well-ventilated place. During use or storage, please pay attention to ignition and avoid contact with oxidizing agents.
Last Update:2024-04-09 21:04:16