Fmoc-Met(O2)-OH - Names and Identifiers
Fmoc-Met(O2)-OH - Physico-chemical Properties
Molecular Formula | C20H21NO6S
|
Molar Mass | 403.45 |
Density | 1.359 |
Boling Point | 709.5±60.0 °C(Predicted) |
Appearance | Powder |
Color | White |
pKa | 3.52±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Fmoc-Met(O2)-OH - Risk and Safety
WGK Germany | WGK 2 water endanger |
HS Code | 2930 90 98 |
Fmoc-Met(O2)-OH - Introduction
Fmoc-Met(O2)-OH(Fmoc-L-Cysteine sulfoxide) is an organic compound with the following properties:
1. Appearance: colorless crystal or white solid.
2. Solubility: Soluble in organic solvents such as methanol, chloroform and dimethyl sulfoxide, slightly soluble in water.
3. Melting Point: about 105-107 degrees Celsius.
Fmoc-Met(O2)-OH has a wide range of uses in the field of chemistry and biochemistry, mainly including the following aspects:
1. Oligopeptides and protein synthesis: As raw materials for proteins or oligopeptides, it can be used to synthesize polypeptides and proteins with specific structures and functions.
2. Synthesis of bioactive substances: In pharmaceutical research, it can be used to synthesize bioactive drugs and compounds, such as anti-tumor drugs.
3. Biochemical analysis: used to study the structure and function of proteins, as well as the mechanism of protein interaction.
4. Protein modification: In the field of protein modification and functional regulation, it can be used for oxidative modification of specific sites or the study of ion channels.
A common method for preparing Fmoc-Met(O2)-OH is:
1. First, L-methionine is reacted with ammonium nitrite to generate L-methionine nitrosoester.
2. Then, L-methionine nitrosoester is reacted with Fmoc-Cl to produce Fmoc-L-methionine nitrosoester.
3. Finally, Fmoc-L-methionine nitrosoester is reduced under alkaline conditions to generate Fmoc-Met(O2)-OH.
Note the following safety information when using Fmoc-Met(O2)-OH:
1. May be irritating to the eyes, skin and respiratory tract, should avoid contact.
2. In use to wear appropriate protective equipment, such as gloves, protective glasses and protective masks.
3. Should be operated in a well-ventilated laboratory.
4. Avoid contact with the fire source, stored away from the fire and oxidant.
5. Carefully read and understand the relevant safety technical instructions before use.
Last Update:2024-04-09 21:01:54