Fmoc-N-methyl-PEG3-CH2CH2COOH
Fmoc-N-methyl-PEG3-CH2CH2COOH
CAS: 1807518-77-9
Molecular Formula: C25H31NO7
Fmoc-N-methyl-PEG3-CH2CH2COOH - Names and Identifiers
Fmoc-N-methyl-PEG3-CH2CH2COOH - Physico-chemical Properties
| Molecular Formula | C25H31NO7 |
| Molar Mass | 457.52 |
| Density | 1.218±0.06 g/cm3(Predicted) |
| Boling Point | 630.5±55.0 °C(Predicted) |
| pKa | 4.28±0.10(Predicted) |
| Storage Condition | 2-8°C，干燥，密封 |
| MDL | MFCD29918264 |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Fmoc-N-methyl-PEG3-CH2CH2COOH - Reference Information
| biological activity | Fmoc-N-methyl-PEG3-CH2CH2COOH is a degradable ADC linker used in antibody drug conjugate (ADC) synthesis. Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker and can be used in the synthesis of PROTAC. |
Last Update：2024-04-09 21:04:16
