Fmoc-Tyr(H2Po3)-Oh
Fmoc-O-Phospho-L-tyrosine
CAS: 147762-53-6
Molecular Formula: C24H22NO8P
Fmoc-Tyr(H2Po3)-Oh - Names and Identifiers
| Name | Fmoc-O-Phospho-L-tyrosine |
| Synonyms | FMOC-TYR(H2PO3)-OH Fmoc-Tyr(Po3H2)-Oh Fmoc-L-Tyr(Po3-H2) Fmoc-Tyr(H2Po3)-Oh FMOC-L-TYR(PO3-H2) FMOC-TYR(PO3H2)-OH FMOC-L-TYR(PO3H2)-OH Fmoc-L-Tyr(Po3H2)-Oh FMOC-O-PHOSPHO-TYR-OH Fmoc-O-Phospho-Tyr-OH Fmoc-Tyrosine(Po3H2)-Oh FMOC-TYROSINE(PO3H2)-OH FMOC-O-PHOSPHO-L-TYROSINE Fmoc-O-Phospho-L-tyrosine Nα-Fmoc-O-phospho-L-tyrosine N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Phosphotyrosine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-phosphono-L-tyrosine |
| CAS | 147762-53-6 |
| InChI | InChI=1/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m0/s1 |
| InChIKey | AMXUJIHSMANWDW-QFIPXVFZSA-N |
Fmoc-Tyr(H2Po3)-Oh - Physico-chemical Properties
| Molecular Formula | C24H22NO8P |
| Molar Mass | 483.41 |
| Density | 1.464±0.06 g/cm3(Predicted) |
| BRN | 6674324 |
| pKa | 1.27±0.30(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.65 |
| MDL | MFCD00235902 |
| Physical and Chemical Properties | Storage Conditions:? 20℃ WGK Germany:3 |
Fmoc-Tyr(H2Po3)-Oh - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29224999 |
Fmoc-Tyr(H2Po3)-Oh - Introduction
Fmoc-O-Phospho-L-tyrosine is a chemical intermediate with the following properties:
1. Appearance: white crystal or crystalline powder.
2. Solubility: can be dissolved in organic solvents, such as dimethylformamide (DMF), dichloromethane and the like.
3. Stability: Stable under dry conditions, but susceptible to hydrolysis and loss of activity in a humid environment.
Fmoc-O-Phospho-L-tyrosine are used in the synthesis and modification of proteins and peptides in organic synthesis. Its Main uses include:
1. Protein synthesis: as a protective group, it can be used for the synthesis and introduction of amino acids.
2. Protein modification: It can be used as a modification reagent for certain tyrosine residues, such as the introduction of phosphate groups.
Fmoc-O-Phospho-L-tyrosine preparation method can be completed by the following steps:
1. Preparation of Fmoc-Tyrosine: Fmoc-tyrosine was obtained by reacting Fmoc-chloroformate with L-tyrosine under alkaline conditions.
2. Phosphorylation: Reaction of Fmoc-tyrosine with dichloromethyl phosphate under alkaline conditions to generate Fmoc-O-Phospho-L-tyrosine.
When using and handling Fmoc-O-Phospho-L-tyrosine, there are several safety information to note:
1. Wear appropriate personal protective equipment such as lab gloves, goggles and lab clothes when operating.
2. Avoid inhalation or contact with skin and eyes during operation.
3. Should be operated in a well-ventilated laboratory to avoid toxic gases.
4. Avoid contact with strong oxidants and strong acids to avoid triggering dangerous reactions.
It should be noted that the above information is for reference only, and the specific use and treatment methods should be adjusted according to the actual situation and experimental requirements.
1. Appearance: white crystal or crystalline powder.
2. Solubility: can be dissolved in organic solvents, such as dimethylformamide (DMF), dichloromethane and the like.
3. Stability: Stable under dry conditions, but susceptible to hydrolysis and loss of activity in a humid environment.
Fmoc-O-Phospho-L-tyrosine are used in the synthesis and modification of proteins and peptides in organic synthesis. Its Main uses include:
1. Protein synthesis: as a protective group, it can be used for the synthesis and introduction of amino acids.
2. Protein modification: It can be used as a modification reagent for certain tyrosine residues, such as the introduction of phosphate groups.
Fmoc-O-Phospho-L-tyrosine preparation method can be completed by the following steps:
1. Preparation of Fmoc-Tyrosine: Fmoc-tyrosine was obtained by reacting Fmoc-chloroformate with L-tyrosine under alkaline conditions.
2. Phosphorylation: Reaction of Fmoc-tyrosine with dichloromethyl phosphate under alkaline conditions to generate Fmoc-O-Phospho-L-tyrosine.
When using and handling Fmoc-O-Phospho-L-tyrosine, there are several safety information to note:
1. Wear appropriate personal protective equipment such as lab gloves, goggles and lab clothes when operating.
2. Avoid inhalation or contact with skin and eyes during operation.
3. Should be operated in a well-ventilated laboratory to avoid toxic gases.
4. Avoid contact with strong oxidants and strong acids to avoid triggering dangerous reactions.
It should be noted that the above information is for reference only, and the specific use and treatment methods should be adjusted according to the actual situation and experimental requirements.
Last Update：2024-04-09 21:21:28
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Product Name: Fmoc-O-Phospho-Tyr-OH Visit Supplier Webpage Request for quotationCAS: 147762-53-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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