Fmoc-Val-Ala-PAB-OH - Names and Identifiers
Fmoc-Val-Ala-PAB-OH - Physico-chemical Properties
Molecular Formula | C30H33N3O5
|
Molar Mass | 515.6 |
Melting Point | 218 °C(dec.) |
Solubility | DMSO: 10 mM( < 1 mg/ml refers to the product slightly soluble or insoluble) |
Storage Condition | -20℃ |
Use | Fmoc-Val-Ala-PAB-OH is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC). |
Target | ADCs Linker |
In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
In vivo study | The ADC is composed of an antibody, and the ADC cytotoxin is bound to the antibody via the ADC linker. |
Fmoc-Val-Ala-PAB-OH - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 1.939 ml | 9.697 ml | 19.395 ml |
5 mM | 0.388 ml | 1.939 ml | 3.879 ml |
10 mM | 0.194 ml | 0.97 ml | 1.939 ml |
5 mM | 0.039 ml | 0.194 ml | 0.388 ml |
Last Update:2024-01-02 23:10:35
Fmoc-Val-Ala-PAB-OH - Introduction
Fmoc-Val-ala-PAB is an organic compound with the chemical formula C12H15N3O2. The following is a description of the nature, use, preparation and safety information of the Fmoc-Val-ala-PAB:
Nature:
-Appearance: Fmoc-Val-ala-PAB in the form of a white or white-like solid.
-Solubility: It is soluble in some organic solvents, such as methanol, dimethyl sulfoxide and dichloromethane.
Use:
- Fmoc-Val-ala-PAB is widely used in the pharmaceutical field of drug research and development.
-It has anti-inflammatory and anti-tumor activities, and is used to develop new drug treatment options.
Preparation Method:
-The preparation of this compound is more complex and usually requires an organic synthetic chemist to synthesize it.
-The preparation process may use a variety of synthetic routes, such as reaction, structural modification and purification.
Safety Information:
-The safe use and handling of Fmoc-Val-ala-PAB must follow chemical safety practices.
-This compound may be toxic to humans, so proper safety measures such as gloves, glasses and protective clothing should be taken when handling.
-Before use, you should understand the toxicity data and safe handling methods of the compound, and ensure that it is operated in a suitable laboratory environment.
- Fmoc-Val-ala-PAB also need to be stored in a cool, dry, well-ventilated place, and away from fire and flammable substances.
Last Update:2024-04-09 20:49:11