Fmoc-p-amino-Phe(Boc)-OH

Fmoc-p-amino-Phe(Boc)-OH - Names and Identifiers

Name	Fmoc-p-amino-Phe(Boc)-OH
Synonyms	RARECHEM BK PT 0176 FMOC-PHE(4-NHBOC)-OH Fmoc-Phe(4-NHBoc)-OH Fmoc-L-4-aminophe(Boc) Fmoc-P(Nh-Boc)-L-Phe-Oh Fmoc-p-amino-Phe(Boc)-OH Fmoc-4-(Boc-amino)-L-phenylalanine (S)-FMOC-(4-BOC-AMINO)PHENYLALANINE 4-Amino-L-phenylalanine, N-FMOC protected N-ALPHA-FMOC-L-4-(BOC-AMINO)-PHENYLALANINE fmoc-l-4-t-butyloxycarbonylaminophenylalanine 4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-4-AMINO-N-T-BUTOXYCARBONYL-L-PHENYLALANINE 4-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-4-TERT-BUTYLOXYCARBONYLAMINO-L-PHENYLALANINE 3-(4-TERT-BUTOXYCARBONYLAMINO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID
CAS	174132-31-1
InChI	InChI=1/C24H22N2O4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14,25H2,(H,26,29)(H,27,28)/t22-/m0/s1

Fmoc-p-amino-Phe(Boc)-OH - Physico-chemical Properties

Molecular Formula	C29H30N2O6
Molar Mass	502.56
Density	1.280±0.06 g/cm3(Predicted)
Boling Point	671.0±55.0 °C(Predicted)
Flash Point	359.9°C
Vapor Presure	5.97E-19mmHg at 25°C
pKa	3.80±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.658

Fmoc-p-amino-Phe(Boc)-OH - Risk and Safety

Hazard Symbols	Xi - Irritant
HS Code	29225090
Hazard Class	IRRITANT

Fmoc-p-amino-Phe(Boc)-OH - Introduction

Fmoc-p-amino-Phe(Boc)-OH is an important amino acid derivative. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
Fmoc-p-amino-Phe(Boc)-OH is a white granular solid with high solubility. It is an unnatural amino acid with good stability and chemical activity.

Use:
Fmoc-p-amino-Phe(Boc)-OH is commonly used to prepare polypeptides and proteins by solid-phase synthesis. It can be used as a functional group to protect amino acids and protect the reactivity of other amino acids in chemical synthesis reactions to ensure the correct assembly of the target peptide chain. In addition, it can also be used as a biologically active mimetic for the study and design of polypeptide molecules with specific functions.

Method:
The preparation of Fmoc-p-amino-Phe(Boc)-OH is generally carried out by synthetic chemical methods. Specifically, L-4-tert-butoxycarbonylaminophenylalanine is first reacted with Fmoc-OSu (a protected Fmoc acyl group) to produce Fmoc-p-amino-Phe(Boc)-OH. Then, the final product is obtained by a series of steps of extraction, purification and drying.

Safety Information:
Fmoc-p-amino-Phe(Boc)-OH is relatively safe under proper use and storage conditions. However, like most chemicals, it still needs to be handled and used properly. Wear appropriate personal protective equipment to avoid contact with skin and eyes. Also prevent inhalation or ingestion of the chemical. During storage, it should be stored in a dry, cool place, away from fire and oxidizing agents. In addition, read and follow the relevant safety practices and procedures.

Last Update：2024-04-09 20:52:54