Folate-PEG-DSPE - Names and Identifiers
Folate-PEG-DSPE - Physico-chemical Properties
Folate-PEG-DSPE - Introduction
Folate-PEG-DSPE(Folate-PEG-DSPE) is a drug delivery vehicle with a specific structure. It is a complex of folic acid, polyethylene glycol (PEG) and phospholipid (DSPE).
In terms of properties, Folate-PEG-DSPE has good water solubility and biocompatibility. It can be stable under physiological conditions and has a longer blood circulation time, so that the drug can be more effectively delivered in the body.
Folate-PEG-DSPE are primarily used in drug delivery systems. The folate molecule is capable of specifically binding to the folate receptor, which is overexpressed on the cell surface. Due to the over-expression of folate receptors on the surface of many tumor cells, Folate-PEG-DSPE can be used to achieve targeted delivery to tumor cells and improve the efficacy of drugs.
On the preparation method, the synthesis of Folate-PEG-DSPE mostly adopts a simple chemical synthesis method. First, folic acid, polyethylene glycol and phospholipids were mixed in a certain molar ratio to react, and the target product was synthesized by controlling the temperature, pH value and reaction time.
In terms of safety, Folate-PEG-DSPE generally have lower toxicity and side effects when used in vivo. However, the specific side effects are dependent on the dose and the specific use. For individual differences and precautions in drug formulation, it is recommended to use and manage under the guidance of a doctor or professional.
Last Update:2024-04-10 22:30:50