GCDC
Glycochenodeoxycholic Acid
CAS: 640-79-9
Molecular Formula: C26H43NO5
GCDC - Names and Identifiers
GCDC - Physico-chemical Properties
| Molecular Formula | C26H43NO5 |
| Molar Mass | 449.62 |
| Density | 1.162±0.06 g/cm3(Predicted) |
| Boling Point | 655.6±40.0 °C(Predicted) |
| Solubility | Almost insoluble (0.016g/L) (25°C) |
| Appearance | Powder |
| pKa | 3.58±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD00271498 |
| Physical and Chemical Properties | Bioactive Glycochenodeoxycholic acid is a bile salt formed in the liver by chenodeoxycholate and glycine. It is a detergent that dissolves fat and promotes absorption. |
GCDC - Reference
| Reference Show more | 1. Li Yaqi, Wang Zixuan, Guan Yanling, etc. Determination of two main binding bile acids in Hugan Pian by HPLC-ELSD [J]. China pharmacist, 2019, 022(002):350-352. 2. Wang, Tianyang, et al. "Metabologic profile indications of serum, lung, bronch of lavage fluid, split and feces in LPS-induced acute lung injury rats based on HPLC-ESI-QTOF-MS." Analytical and bioanalytical chemistry 412.5 (2020): 1215-1234. 3. Wang, Tianyang, et al. "Metabolomic profile perturbations of serum, lung, bronchoalveolar lavage fluid, spleen and feces in LPS-induced acute lung injury rats based on HPLC-ESI-QTOF-MS." Analytical and bioanalytical chemistry 412.5 (2020): 1215-1234. 4. [IF=3.935] Ziying Liu et al."Promotion of classic neutral bile acids synthesis pathway is responsible for cholesterol-lowing effect of Si-miao-yong-an decoction: Application of LC-MS/MS method to determine 6 major bile acids in rat liver and plasma."J Pharmaceut Bio 5. [IF=5.396] Shiming Huang et al."A sulfated polysaccharide from Gracilaria Lemaneiformis regulates cholesterol and bile acid metabolism in high-fat diet mice."Food Funct. 2019 Jun;10(6):3224-3236 6. [IF=5.396] Cong Liang et al."Lactiplantibacillus plantarum H-87 prevents high-fat diet-induced obesity by regulating bile acid metabolism in C57BL/6J mice."Food Funct. 2021 May;12(10):4315-4324 7. [IF=5.34] Kaihui Zhang et al."A UPLC-MS/MS-based metabolomics analysis of the pharmacological mechanisms of rabdosia serra against cholestasis."Phytomedicine. 2021 Oct;91:153683 8. [IF=3.935] Song Lin et al."A systemic combined nontargeted and targeted LC-MS based metabolomic strategy of plasma and liver on pathology exploration of alpha-naphthylisothiocyanate induced cholestatic liver injury in mice."J Pharmaceut Biomed. 2019 Jul;171:180 9. [IF=3.935] Runjing Zhang et al."Xiaoyan lidan formula ameliorates α-naphthylisothiocyanate-induced intrahepatic cholestatic liver injury in rats as revealed by non-targeted and targeted metabolomics."J Pharmaceut Biomed. 2020 Feb;179:112966 10. [IF=5.396] Juan Wu et al."Sargassum fusiforme polysaccharide is a potential auxiliary substance for metformin in the management of diabetes."Food Funct. 2022 Feb;: 11. [IF=6.558] Yan Cao et al."Widely quasi-quantitative analysis enables temporal bile acids-targeted metabolomics in rat after oral administration of ursodeoxycholic acid."ANALYTICA CHIMICA ACTA. 2022 Jun;1212:339885 |
GCDC - Uses and synthesis methods
Target
Human Endogenous Metabolite
Last Update：2024-04-09 20:52:54
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Email: sales@medchemexpress.com
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Product Name: Glycochenodeoxycholic Acid Visit Supplier Webpage Request for quotationCAS: 640-79-9
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