Name | Geraniin |
Synonyms | eraniin GERANIIN Geraniin B-D-GLUCOPYRANOSE 5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-Methano-2H-1-benzoxocin-5,7-dicarboxylate)cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate)1-(3,4,5-trihydroxybenzoate), stereoisoMer |
CAS | 60976-49-0 |
Molecular Formula | C41H28O27 |
Molar Mass | 952.64 |
Density | 2.25 |
Melting Point | 360°C |
Specific Rotation(α) | (c, 0.5 in MeOH)-141 |
Solubility | DMSO : 100 mg/mL (104.97 mM; Need ultrasonic) |
Appearance | White dry powder |
pKa | 6.35±0.70(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
MDL | MFCD09038731 |
Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Euphorbiaceae, Phyllanthus Phyllanthus urinaria L. whole grass. |
Reference Show more | 1. Zhang Fan, Ren Zhen, elegant, etc. Protective effect of geraniin on liver injury induced by carbon tetrachloride in mice based on TLR-4/NF-κB signaling pathway [J]. Chinese herbal medicine, 2018. 2. Li Jia Ni, Li Zi Meng, elegant, etc. Protective effect and mechanism of geraniin on D-galactosamine-induced liver injury in mice [J]. Chinese Journal of Experimental prescriptions, 2019, 29 (15):116-121. 3. Wu Lingfang, Liang Wenyi, Zhang Lanzhen. Study on the determination of main components in Tibetan medicine Phyllanthus emblica [J]. World Science and Technology-modernization of traditional Chinese medicine, 2020,22(08):2857-2863. 4. [IF = 2.928] Dan Huang et al. Geraniin protection bone row-derived mesenchymal stem cells against hydrogen peroxide-induced cellular oxidative stress in vitro."Int J Mol Med. 2018 Feb;41(2):739-748 |
distribution | , geraniins were also detected in the families of naliaceae and dunaliaceae, and concentrated in the genus geranium of calcareous family and the genus Phyllanthus of Euphorbiaceae, moreover, the distribution of geraniin in the seedling family of alpinaceae is wider than that in Euphorbiaceae.|
effect | geraniin has high antioxidant activity in vitro, scavenging DPPH free radicals, hydroxyl radicals, superoxide radical. |
Last Update:2024-04-09 20:49:11
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